Results 61 to 70 of about 25,640,457 (357)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Spatial and Temporal Evolution Pattern of Water Conservation Function of Ningxia Province and Its Attribution Analysis

Shuitu Baochi Xuebao
［Objective］ To assess the water conservation capacity of the upper Yellow River region, and to provide a scientific basis for the ecological protection and high-quality development of the Yellow River basin.
WANG Peng, MA Yilun, CHENG Jing, XU Mingxiang, SU Shengliang, PU Yong, HAN Lei, YANG Fang   +7 more
doaj   +1 more source

Risk Assessment and Zoning on Supply and Demand of Water Yield Services in Pakistan Section of China-Pakistan Economic Corridor

Shuitu baochi tongbao, 2023
[Objective] The supply and demand of water yield services in the Pakistan section of China-Pakistan economic corridor were analyzed, the risk areas for water yield services were identified scientifically, and the risk prevention measures were formulated ...
Zhong Mengjun, Jiang Guiguo, Lu Yiwen, Cheng Zhenni, Dong Weiwei   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Spatial–Temporal Changes and Prediction of Carbon Storage in the Tibetan Plateau Based on PLUS-InVEST Model

Forests, 2023
The changes in the recent and future spatial–temporal patterns of carbon storage of the Tibetan Plateau and its dominant factors in different periods were unclear, and were conducive to optimizing the spatial layout of land.
Huihui Zhao, Bing Guo, Guojun Wang
semanticscholar   +1 more source

Spatio-temporal variation and prediction of land use and carbon storage in high groundwater level mining area

Meitan kexue jishu
Mining activities and urbanisation in high dive mining areas can lead to significant changes in land use types, which in turn affect the carbon sequestration capacity of mining areas.
Liangji XU, Zhendong HE, Xiaopeng LIU, Kun ZHANG, Manyi WU   +4 more
doaj   +1 more source

Spatio-temporal Evolution and Scenario Prediction of Carbon Storage in Typical Wetlands in Poyang Lake Region

Shuitu baochi tongbao, 2023
[Objective] The temporal and spatial characteristics of carbon storage in the Poyang Lake wetland ecosystem were analyzed in order to provide scientifically based recommendations to protect Poyang Lake wetlands in the future and to produce regional ...
Wei Zezhu, Dong Bin, Xu Haifeng, Xu Zhili, Lu Zhipeng, Liu Xiao   +5 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Geospatial mapping of carbon estimates for forested areas using the InVEST model and Sentinel-2: A case study in Galicia (NW Spain).

Science of the Total Environment
CO2 emissions have increased exponentially in recent years, so measuring and quantifying carbon sequestration is a step towards sustainable forest management and combating climate change. The overall goal of this study is to develop an accurate model for
Mario García-Ontiyuelo, Carolina Acuña-Alonso, Enrique Valero, X. Álvarez   +3 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source