Results 61 to 70 of about 1,387,394 (314)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Effects of land-use and climate change on sediment and nutrient retention in Guizhou, China
Ecosystem Health and Sustainability, 2020 Introduction Sediment and nutrient retention have significant impacts on agricultural productivity and water quality. Obvious changes of climate and land-use have deeply affected freshwater ecosystem services in the last several decades.
Huiqing Han +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
High speed rail transport valuation and policy decisions [PDF]
, 2008 The present paper investigates the process of decision making regarding the optimal timing to invest in the high speed rail (HSR) project, under uncertainty, using the real options analysis (ROA) framework. It’s developed a continuous time framework that
Azevedo-Pereira, José +2 more
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Assessment of soil erosion and its driving factors in the Huaihe region using the InVEST-SDR model
Geocarto International, 2023 Aiming to provide a scientific basis for the prevention and control of soil erosion in the Huaihe region, this study uses the InVEST-SDR model to estimate the temporal and spatial changes of soil erosion and soil conservation in the Huaihe region in 2010,
Ziqi Guo +6 more
doaj +1 more source
Multi-asset minority games [PDF]
, 2006 We study analytically and numerically Minority Games in which agents may invest in different assets (or markets), considering both the canonical and the grand-canonical versions.
Bianconi, Ginestra +3 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Ben-Porath meets Lazear: lifetime skill investment and occupation choice with multiple skills [PDF]
, 2017 We develop a fairly general and tractable model of investment when workers can invest in multiple skills and different jobs put different weights on those skills.
Cavounidis, Costas, Lang, Kevin
core
A model of collateral, investment, and adverse selection [PDF]
Journal of Economic Theory, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources