Results 71 to 80 of about 23,565,951 (358)
Research on habitat quality change is of great significance for regional ecological security. Analysis of spatiotemporal change of habitat quality based on different geomorphic types can restore the background of ecological environment in historical ...
Baixue Wang, W. Cheng
semanticscholar +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Coupling PLUS–InVEST Model for Ecosystem Service Research in Yunnan Province, China
In efforts to improve regional ecosystem service functions, coordinate land development and ecological conservation, and establish a reference for optimizing land resource allocation and policy formulation to cope with climate change, it is critical to ...
Rongyao Wang +5 more
semanticscholar +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
[Objective] This study aimed to investigate the spatiotemporal changes and trade-offs/synergies of ecosystem services within the Beiluo River basin to provide a scientific foundation for rational resource allocation and sustainable development. [Methods]
ZHANG Yujie +5 more
doaj +1 more source
Water yield is a key ecosystem function index, directly impacting the sustainable development of the basin economy and ecosystem. Climate and land use/land cover (LULC) changes are the main driving factors affecting water yield.
Pei-Rei Wei +6 more
semanticscholar +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Land use/land cover change has a significant indicative effect on the carbon storage of terrestrial ecosystems. We selected Chang-Zhu-Tan urban agglomeration as the research object, coupled FLUS and InVEST models to explore the changes in land use and ...
Weiyi Sun, Xianzhao Liu
semanticscholar +1 more source
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
[Objective] The temporal and spatial change characteristics of a soil conservation function in Southern Jiangxi Province were analyzed in order to provide a scientific basis for improving soil conservation capacity and maintaining an ecological security ...
Luo Chengkang +5 more
doaj +1 more source

