Results 101 to 110 of about 110,805 (249)

Development of Betalactam‐Predictor: A Clinical Decision Tool for Delabeling Low‐Risk Betalactam Allergy Patients. Initial Validation in Penicillin Allergy

Allergy, EarlyView.
BL‐Predictor has emerged as a new tool for delabeling penicillin allergy. External validation has shown a specificity of 93% for detecting low‐risk patients. This score could potentially reduce diagnostic costs and the negative consequences associated with incorrect antibiotic allergy labels.
Marina Labella, Rafael Nuñez, Inmaculada Doña, Julia Rodríguez de Guzmán, Esther Moreno, Lene Heise Garvey, Jose Julio Laguna, Annick Barbaud, Patrizia Bonnadona, Jonas Bredtoft Boel, Holger Mosbech, Giovanna Sfriso, Mariana Castells, Elizabeth Phillips, María José Torres   +14 more
wiley   +1 more source

Structure of communities in semantic networks of biomedical research on disparities in health and sexism [PDF]

Biomedica, 2020
Rivera-Romano LS, Juárez-Cano G, Hernández-Lemus E, Vallejo M, Martínez-García M.   +4 more
europepmc   +1 more source

Behavioral traits predicting cocaine-conditioned place reference in mice: role of anxiety adn the basolateral amygdala [PDF]

, 2016
Aims. The individual susceptibility to cocaine addiction, a factor of interest in the understanding and prevention of this disorder, may be predicted by certain behavioral traits.
Castilla-Ortega, Estela, Estivill-Torrús, Guillermo, Ladrón de Guevara-Miranda, David, Pavón, Francisco Javier, Rivera, Patricia, Rodríguez de Fonseca, Fernando, Santin-Nuñez, Luis Javier, Serrano, Antonia, Suárez, Juan   +8 more
core  

Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy

Allergy, EarlyView.
DeAns with defined nanoscale structure reveal that conjugate size and determinant density govern IgE‐mediated effector‐cell activation in AX allergy. All DeAn generations bind to sIgE in inhibition immunoassay, but only larger DeAns trigger FcεRI‐dependent responses in mouse MC, huRBL‐2H3, and LUVA cells.
Amene Tesfaye Ayane, Maria Salas, Sara Benede, Maria J. Rodriguez‐Sanchez, Maria J. Rodriguez‐Sojo, Isabel M. Jiménez‐Sánchez, Gador Bogas, Ezequiel Perez‐Inestrosa, Cristobalina Mayorga, Juan L. Paris, Alba Rodríguez‐Nogales, María J. Torres, María I. Montañez   +12 more
wiley   +1 more source

Investigación biomédica en seres humanos

Revista Cubana de Higiene y Epidemiología
Motivados por el impetuoso y eficaz avance alcanzado por nuestro país en los últimos años en el desarrollo científico, se realizó una revisión bibliográfica sobre los antecedentes y aspectos fundamentales de la investigación biomédica en seres humanos ...
Plácido Pedroso Flaquet
doaj  

Successful Application of the Mast Cell Activation Test in Immediate Hypersensitivity to Amoxicillin

Allergy, EarlyView.
This study included 28 amoxicillin‐allergic patients and 11 healthy exposed controls. Mast cells were differentiated from CD34+ progenitors over 8 weeks using cytokine cocktails. The mast cell activation test involved sensitization with patient or control sera and stimulation with free amoxicillin or G4/G5‐AXO dendrimers with successfully activated ...
Jose A. Céspedes, Clara Lebrón‐Martín, Lucía Vallecillos‐Azor, Pablo Torres, Amene Tesfaye Ayane, Gádor Bogas, María Salas, Adriana Ariza, María Isabel Montañez, María José Torres, Carlos José Aranda, Cristobalina Mayorga   +11 more
wiley   +1 more source

Estimates of the likelihood of threats are related to intolerance of uncertainty and learning [PDF]

, 2018
In the present experiment, we assessed the relationship between intolerance of uncertainty and expectancy ratings of threats both in the presence of conditioned stimuli (CS) that signalled the delivery of an aversive unconditioned stimulus (US), and ...
Cobos-Cano, Pedro Luis, Flores Martín, Amanda, Gómez, Diana, López-Gutiérrez, Francisco José   +3 more
core  

Neuropathological events in an animal model resembling human fetal post-hemorrhagic hydrocephalus [PDF]

, 2019
Introduction: In premature newborns, intraventricular hemorrhages (IVH) probably trigger the disruption of the neurogenic ventricular zone. Most of the cases with severe IVH develop post-hemorrhagic hydrocephalus (PHH).
Jimenez-Lara, Antonio Jesus, Ojeda-Pérez, Betsaida, Páez-González, Patricia   +2 more
core  

The Testicular Cancer Consortium (TECAC): Filling Knowledge Gaps in the Genetic Etiology of Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The Testicular Cancer Consortium (TECAC) was established in 2012 and is comprised of researchers from over 25 centers in Europe and North America. TECAC's overarching goal is to investigate the genetic susceptibility of testicular germ cell tumors (TGCT) to better understand their biology, impact prevention strategies, and inform ...
Peter A. Kanetsky, Kristian Almstrup, Svetlana Cherlin, Victoria K. Cortessis, Alberto Ferlin, Jourik A. Gietema, Anna González‐Neira, Tom Grotmol, Robert J. Hamilton, Trine B. Haugen, Lambertus A. Kiemeney, Jung Kim, Csilla Krausz, Davor Lessel, Ragnhild A. Lothe, Kevin T. Nead, Jérémie Nsengimana, Jenny N. Poynter, Ewa Rajpert‐DeMeyts, Lorenzo Richiardi, Stephen M. Schwartz, Rolf I. Skotheim, Douglas R. Stewart, Clare Turnbull, Fredrik Wiklund, Tongzhang Zheng, Katherine L. Nathanson, Katherine A. McGlynn, for the Testicular Cancer Consortium   +28 more
wiley   +1 more source

Long-term Impact of Cenobamate on Cognition in Patients with Drug-Resistant Focal Epilepsy: Outcomes from an Exploratory Real-World Study

Neurology and Therapy
Introduction Cognitive adverse events are a common issue in patients receiving later-generation antiseizure medications (ASMs). In this study, we assessed the long-term effects of cenobamate on cognitive endpoints in patients with drug-resistant focal ...
Teresa Ramirez-Garcia, Pablo Cabezudo-Garcia, Guillermina Garcia-Martin, Yolanda Lopez-Moreno, Alvaro Sanchez-Guijo, Juan De La Parra, Pedro J. Serrano-Castro   +6 more
doaj   +1 more source