Results 111 to 120 of about 54,072 (237)

Maternal deprivation and adolescent alcohol exposure induce sex-dependent alterations in stress-related behavior and lipid signaling in rats

Biology of Sex Differences
Background Early-life stress constitutes a major risk factor for the development of neuropsychiatric and substance use disorders, exerting enduring effects on stress responsivity and emotional behavior.
Laura Sánchez-Marín, Adriana Castro-Zavala, María Flores-López, Ana Gavito, Raquel Reviriego, Eva M. Marco, Francisco J. Pavón-Morón, Fernando Rodríguez de Fonseca, Antonia Serrano   +8 more
doaj   +1 more source

Nut Consumption and Sperm Quality in Healthy Men: Results From the Led‐Fertyl Study

Andrology, EarlyView.
ABSTRACT Background Nuts are rich in antioxidants and other bioactive compounds, and recent evidence suggests that their regular consumption may be associated with sperm quality. However, the current scientific evidence remains limited and inconsistent.
Estefanía Dávila‐Córdova, Nancy Babio, Cristina Valle‐Hita, María Fernández de la Puente, Alfonso Beltran‐Arasa, Miguel Cebrián‐Puig, Violeta Fambuena‐Perez, Iván García‐Serrano, Michelle M. Murphy, Jordi Salas‐Salvadó, Albert Salas‐Huetos   +10 more
wiley   +1 more source

Automated identification of MRI series using a hierarchical modular machine-learning pipeline

European Radiology Experimental
Objective The volume and diversity of large MR imaging datasets require efficient automated labelling tools for cataloguing MR series, as manual annotation is impractical and costly.
Mariusz J. Kujawa, Matías Fernández‑Patón, Leonor Cerdá Alberich, Diana Veiga-Canuto, Luis Martí‑Bonmatí   +4 more
doaj   +1 more source

Programa de las X Jornadas de Aspectos Éticos de la Investigación Biomédica.

Programa de las X Jornadas de Aspectos Éticos de la Investigación ...
Instituto de Salud Carlos III. Comité de Ética de la Investigación
core  

APROXIMACIONES BIOINFORMÁTICAS EN INVESTIGACIÓN BIOMÉDICA: APLICACIONES Y PERSPECTIVAS

Importantes avances en técnicas de biología molecular y genética han hecho posible la obtención de grandes volúmenes de datos biológicos. De manera paralela, este incremento en la cantidad y complejidad de información se ha acompañado del desarrollo e ...
Ortega-Recalde, Oscar
core   +1 more source

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

Clinical Burden of Symptomatic HEV‐3 Infection in Southern Spain

Alimentary Pharmacology &Therapeutics, EarlyView.
Clinical burden of symptomatic HEV‐3 infection in southern Spain. Between 2022 and 2025, 1124 patients with acute hepatitis, defined as ALT ≥ 3 times the upper limit of normal and negative screening for HAV, HBV, HCV, EBV and CMV, were evaluated in Andalusia.
María Casares‐Jimenez, Claudia Ferreira‐Tata, Isabel Viciana, Carolina Freyre‐Carrillo, Pedro Lopez‐Lopez, Ana Belen Perez, Berta Becerril‐Carral, Ana Fuentes, Juan Macías, Lucia Rios‐Muñoz, Francisco Franco‐Alvarez de Luna, María Teresa Cabezas‐Fernandez, Diana Corona‐Mata, Antonio Rivero‐Juarez, Antonio Rivero   +14 more
wiley   +1 more source

La asignación de recursos y la investigación biomédica

, 2001
Not availableNadie parece cuestionar, al menos desde el punto de vista teórico, que la Investigación junto con la Docencia, son compañeros inseparables del objetivo último de un Sistema Sanitario moderno y consolidado, que no es otro que el de dar ...
Juan José Artells Herrero, Artells Herrero, Juan José   +1 more
core   +1 more source

Natural History of Recurrent Acute Pancreatitis: Implications for Interventional Trial Design

Alimentary Pharmacology &Therapeutics, EarlyView.
In this nationwide cohort of 6894 patients with recurrent acute pancreatitis, recurrence risk increased progressively with each episode and occurred most frequently within the first year. Successive episodes were separated by shorter intervals, indicating an accelerating disease course and highlighting the importance of early preventive interventions ...
Søren S. Olesen, Niels Henrik Bruun, Line Davidsen, Srdan Novovic, Stig B. Laursen, Enrique de‐Madaria, Dhiraj Yadav, Asbjørn M. Drewes   +7 more
wiley   +1 more source

Cesni‐cel (ARI0002h) in ultra‐high‐risk multiple myeloma with plasma cell leukaemia or central nervous system involvement

British Journal of Haematology, EarlyView.
ARI0002h induced response in 15/17 patients with plasma cell leukaemia (PCL)/central nervous system (CNS)‐multiple myeloma (MM) (87% achieved ≥ very good partial response [VGPR]) with a median progression‐free survival (PFS)/overall survival (OS) of 10.5 and 15.9 months respectively.
Carlos Jimenez‐Mira, Natalia Tovar, Núria Martínez‐Cibrián, Verónica González‐Calle, Nil Albiol, Nieves López‐Muñoz, Aina Oliver‐Caldés, Azucena González, José Miguel Mateos, Marta Español‐Rego, Laura Rosiñol, Manel Juan, Paola Charry, José María Sanchez‐Pina, Sergio Navarro, Daniel Munárriz, Lucía López‐Corral, Valentín Ortiz‐Maldonado, Sara Varea, Eulalia Olesti, Julio Delgado, Álvaro Urbano‐Ispizua, Joaquín Martínez‐López, María Victoria Mateos, Luis Gerardo Rodríguez‐Lobato, Carlos Fernández de Larrea   +25 more
wiley   +1 more source