Results 141 to 150 of about 743,546 (262)
Automatic magnetic resonance imaging series labelling for large repositories
Journal of Big DataLarge medical image repositories present challenges related to unstructured data. A data enrichment process allows the storage of additional information for fast identification of the content and properties of medical imaging studies.
Armando Gomis-Maya +8 more
doaj +1 more source
Historia de la Biomédica en El Salvador. [PDF]
, 2015 La historia de la Biomédica remonta sus orígenes en los años 30´s y 40´s del siglo pasado en países europeos y en Norteamérica, como consecuencia de las necesidades y los problemas derivados de las investigaciones tecnológicas en la salud.
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Acta Ophthalmologica, EarlyView.Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry +27 more
wiley +1 more source
Comentarios a la ley d einvestigación biomédica y al comité de bioética de España [PDF]
, 2008 [Resumen] En este trabajo se describen los contenidos de la Ley de Investigación Biomédica y se analizan críticamente los órganos encargados de autorizar y hacer el seguimiento ético de las investigaciones, como son los Comités de Investigaciones, la ...
Cambrón Infante, Ascensión
core +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.Nationwide implementation of double reflex testing for hepatitis delta in Spain markedly increased anti‐HDV and HDV viral load testing between 2022 and 2024, enabling national seroprevalence estimates. Despite this progress, substantial regional heterogeneity persists, highlighting the need for standardised reflex diagnostic protocols.
Ana Alberola +95 more
wiley +1 more source
“Comercio de autorías”: mala conducta de los autores en la investigación y publicación biomédica
Investigación en Educación Médica, 2023 Joel Alhuay-Quispe
semanticscholar +1 more source
British Journal of Haematology, EarlyView.We show how the loss of activity of the translation initiation factor EIF5A2—either through gene hypermethylation or pharmacologic inhibition of its highly specific hypusine post‐translational modification—induces venetoclax sensitivity in acute myeloid leukaemia (AML) cells.
Eva Crespo‐García +5 more
wiley +1 more source
Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice
Brain Pathology, EarlyView.We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga +11 more
wiley +1 more source
La investigación biomédica sobre abuso de sustancias a través de la base de datos Medline (2006-2010) [PDF]
, 2015 El Abuso de sustancias es uno de los principales problemas sociales y de salud pública a escala mundial. Este estudio analiza la investigación científica sobre los trastornos relacionados con sustancias generado a lo largo del período 2006-2010 así como ...
Agulló Calatayud, Víctor +3 more
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Brain Pathology, EarlyView.A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña +20 more
wiley +1 more source