Results 141 to 150 of about 4,038,876 (172)

Nut Consumption and Sperm Quality in Healthy Men: Results From the Led‐Fertyl Study

open access: yesAndrology, Volume 14, Issue 7, Page 2262-2273, October 2026.
ABSTRACT Background Nuts are rich in antioxidants and other bioactive compounds, and recent evidence suggests that their regular consumption may be associated with sperm quality. However, the current scientific evidence remains limited and inconsistent.
Estefanía Dávila‐Córdova   +10 more
wiley   +1 more source

Ética de la investigación biomédica

open access: yesArbor: Ciencia, Pensamiento y Cultura, 2008
David Rodríguez-Arias
doaj  

The Binding of Fibroblast Growth Factor 23 (FGF23) to FGF Receptor‐αKlotho Complex Increases Sinoatrial Electrical Activity

open access: yesActa Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim This study aims to investigate whether the Fibroblast Growth Factor 23 (FGF23) modulates the electrical activity of sinoatrial (SAN) cells. The canonical function of FGF23 is to regulate body phosphorus and calcium homeostasis by activating the FGF1 receptors (FGFR1)/α‐Klotho complex in the kidney and parathyroid glands.
Giorgia Bertoli   +10 more
wiley   +1 more source

Natural History of Recurrent Acute Pancreatitis: Implications for Interventional Trial Design

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 7, Page 976-984, October 2026.
In this nationwide cohort of 6894 patients with recurrent acute pancreatitis, recurrence risk increased progressively with each episode and occurred most frequently within the first year. Successive episodes were separated by shorter intervals, indicating an accelerating disease course and highlighting the importance of early preventive interventions ...
Søren S. Olesen   +7 more
wiley   +1 more source

IMPROVE 2025: The 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence

open access: yesClinical Obesity, Volume 16, Issue 5, October 2026.
ABSTRACT An international cohort of 161 clinicians and researchers from 19 countries attended the 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence (IMPROVE) in Prague, Czech Republic, on 2–4 July 2025. The aims of the meeting were to advance understanding of hyperphagia and obesity caused by defects in the melanocortin‐4 receptor
Jesús Argente   +17 more
wiley   +1 more source

Leisure‐Time Physical Activity on Age‐Modelled Trajectories of Body Mass Index and Obesity Risk Throughout Life: Multivariable Regression and Mendelian Randomization Analyses Using Electronic Health Record Data From the CORDELIA‐Catalunya Study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8925-8935, October 2026.
ABSTRACT Aims To assess whether self‐reported leisure‐time physical activity, moderate‐to‐vigorous leisure‐time physical activity, and genetically determined cardiorespiratory fitness are associated with age‐related BMI trajectories and incident obesity. Methods We pooled 14 993 adults (30–90 years; 52.7% women; cohorts: REGICOR‐ACRISC, ILERVAS, ARTPER)
Javier Hernando‐Redondo   +13 more
wiley   +1 more source

Real‐World Effectiveness and Safety of Finerenone in People With Type 2 Diabetes and Chronic Kidney Disease: A Spanish Multicentre Retrospective Observational Study (MEDFINE‐RWD)

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9461-9472, October 2026.
ABSTRACT Aim Although finerenone has shown efficacy in randomized trials, evidence from routine clinical practice remains limited. We aimed to assess the real‐world effectiveness and safety of finerenone in people with type 2 diabetes (PWT2D) and chronic kidney disease (CKD), with a particular focus on residual cardiorenal risk as reflected by changes ...
Oscar Moreno‐Pérez   +13 more
wiley   +1 more source

Phase IIB, Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial of Intravenous Defibrotide for the Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome in COVID‐19

open access: yesEuropean Journal of Haematology, Volume 117, Issue 4, Page 922-935, October 2026.
ABSTRACT Introduction Endothelial dysfunction is key in COVID‐19 pathogenesis. This randomized, double‐blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS‐CoV‐2 infection and respiratory failure.
Ruben Jara Rubio   +38 more
wiley   +1 more source

Evaluating Leadership and Teamwork Competency Acquisition Through Clinical Simulation: Development of the Clinical Simulation Learning Leadership and Teamwork Scale

open access: yesJournal of Clinical Nursing, Volume 35, Issue 10, Page 4285-4294, October 2026.
ABSTRACT Advanced simulation is a methodology that allows the development of technical skills and transversal skills such as teamwork and leadership. There are tools to measure the development of technical competencies and student satisfaction with the methodology, but not to measure the development and use of transversal competencies in the clinical ...
Rafael González‐Moret   +6 more
wiley   +1 more source

Liver and Spleen Stiffness as Non‐Invasive Tools Assessing Liver Congestion in Patients With Budd‐Chiari Syndrome

open access: yesLiver International, Volume 46, Issue 10, October 2026.
ABSTRACT Background and Aims Assessing liver congestion and portal hypertension (PHT) in Budd–Chiari syndrome (BCS) remains challenging. We evaluated liver and spleen stiffness measurements (LSM, SSM) obtained by transient elastography as non‐invasive tools for identifying clinically meaningful liver congestion in BCS.
Andreea Fodor   +22 more
wiley   +1 more source

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