Results 151 to 160 of about 743,546 (262)

Cumulative effect of multiple health and social factors on adolescent mental well‐being: a cross‐sectional study in Catalonia

open access: yesChild and Adolescent Mental Health, EarlyView.
Background While numerous studies have explored factors contributing to poor mental health, few have examined the combined influence of multiple health and social factors and their cumulative effect. This study specifically aimed to analyze the cumulative effect of multiple health and social factors associated with poor mental well‐being in school‐aged
Marina Robles‐Muñoz   +7 more
wiley   +1 more source

Finding More in Less: Precision Medicine for Pancreatic Cancer Using Residual Cytology Samples

open access: yesCytopathology, EarlyView.
The study evaluates the use of residual liquid‐based cytology (LBC) samples from pancreatic ductal adenocarcinoma (PDAC) for molecular analysis. It shows that LBC samples preserve nucleic acid quality and remain suitable for next‐generation sequencing (NGS) and MSI testing even after prolonged storage, underscoring their value when other samples are ...
Raquel Antón‐Peñalver   +17 more
wiley   +1 more source

Exploring Perception in Dental Students' Communication Skills: An Online Survey

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Background Effective communication in dentistry is crucial for patient understanding and promoting health. Undergraduate dental education provides a critical opportunity to instil these skills. Objectives To describe the self‐perceptions of undergraduate dental students at Universitat Internacional de Catalunya (Barcelona, Spain) regarding ...
Mireia Cruanyes   +2 more
wiley   +1 more source

[Differentiated review of biomedical research projects by ethics committees]. [PDF]

open access: yesRev Med Chil, 2017
Portales MB   +3 more
europepmc   +1 more source

Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease

open access: yesEpilepsia, EarlyView.
Abstract Background and Objective Lafora disease (LD) is a rare progressive disorder caused by mutations in the EPM2A or EPM2B genes, characterized by the accumulation of Lafora bodies, drug‐resistant epilepsy, and cognitive decline. To investigate the early molecular mechanisms of LD, we studied electrophysiological changes in the dentate gyrus (DG ...
Cinzia Costa   +17 more
wiley   +1 more source

Teleost‐specific ictacalcins exhibit similar structural organization, cation‐dependent activation, and transcriptional regulation as human S100 proteins

open access: yesThe FEBS Journal, EarlyView.
Calcium‐binding S100 proteins are important mediators of inflammation in humans. Distant members of this family have been recently discovered in teleost fish but their resemblance to human proteins has not been explored yet. This study demonstrates that zebrafish‐specific S100i1 and S100i2 (ictacalcins) possess identical structural organization and ...
Liz Hernández   +13 more
wiley   +1 more source

Quality of Dying Among Institutionalised Nursing Home Residents From the Caregivers' Perspective: A Mixed‐Methods Study

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aims To examine how family caregivers of deceased nursing home residents scored and justified their ratings for each item on the Quality of Dying in Long‐Term Care scale and to identify the consistencies and discrepancies between their perceptions and the scores assigned when assessing the residents' end‐of‐life experience. Design A convergent
Daniel Puente‐Fernandez   +5 more
wiley   +1 more source

Universal Dental Adhesives Containing Zinc Oxide and Copper Nanoparticles Improve Interface on Caries‐Affected Dentin After 2 Years: In Vitro Study

open access: yesJournal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective To evaluate the effect of adding zinc oxide and copper nanoparticles (ZnO/CuNp) into universal adhesives (UAs) on resin–dentin microtensile bond strength (μTBS), nanoleakage (NL), and presence of ZnO/Cu within the hybrid layer on caries‐affected dentin, both at baseline (T0) and after 2 years of water storage (T2).
Mario Felipe Gutiérrez   +4 more
wiley   +1 more source

Efficacy of a Multicomponent Intervention for Frailty or Physical Function in Prefrail or Frail Older Adults: FRAILMERIT Multicenter Clinical Trial

open access: yesJournal of the American Geriatrics Society, EarlyView.
Clinical management of the older adult. ABSTRACT Objectives Frailty is a common condition in community‐dwelling older adults with high health and socioeconomic implications. However, primary care‐led randomized trials have been scarcely tested. Design Multicenter cluster randomized clinical trial.
Adriana Abizanda Saro   +86 more
wiley   +1 more source

Multidimensional associations of physical performance, balance, wellness and daily activities with frailty in older adults with coexisting frailty and diabetes

open access: yesJournal of Clinical Nursing, EarlyView.
Abstract Background The coexistence of frailty and type 2 diabetes mellitus in the older population heightens the risk of adverse events. However, research on functional and wellness factors associated with frailty in this population is limited. Purpose To investigate the associations of physical performance, functional dependency, physical activity ...
Juan Corral‐Pérez   +5 more
wiley   +1 more source

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