Results 201 to 210 of about 54,072 (237)

Comparison of Repetition‐Based Progressive‐Overload Strategies in Resistance Training: Rest‐Pause Versus Drop Sets

Scandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 7, July 2026.
ABSTRACT Rest‐pause (RP) and drop sets (DS) are widely used as intensification strategies during resistance training. However, their incorporation within a repetition‐based progressive‐overload (PO) model and their effects under supervised conditions are not well established. We compared progressive‐overload rest‐pause (PO‐RP) with progressive‐overload
Salvador Vargas‐Molina, Alejandro García‐Palumbo, Jorge L. Petro, Diego A. Bonilla, Manuel García‐Sillero, Leandro Carbone, Brad J. Schoenfeld, Javier Benítez‐Porres   +7 more
wiley   +1 more source

Sex Differences in Cardiac Involvement in Adults With Myotonic Dystrophy Type 1: A Multicenter Study. [PDF]

JACC Adv
Alen A, Muñoz C, Soriano-Amores M, de Frutos F, Báez-Ferrer N, Peña-Peña ML, Villacorta E, Ripoll-Vera T, Zorio E, Gimeno AM, Bermúdez-Jiménez J, Limeres J, Tiron C, Martínez-Álvarez E, Cabrera-Romero E, García-Pavía P, Espinosa MA, Piqueras J, García-Hernández S, Palomino-Doza J, Moliner-Abós C, Moris G, Carrillo-Mora LM, Syrris P, Alvarez-Velasco R, Gimeno JR, Lorca R.   +26 more
europepmc   +1 more source

Memoria 2014 Instituto de Investigación Biomédica de A Coruña (INIBIC)Memoria 2014 Instituto de Investigación Biomédica de A Coruña (INIBIC)

, 2017

core  

Co(II), Cu(II), and Ni(II) Coordination Complexes: Synthesis, Characterization, Experimental, and Computational Study on Potential Antiplasmodial Activity

ChemMedChem, Volume 21, Issue 12, 26 June 2026.
Four isostructural complexes (C1–C4) derived from 2‐(tert‐butoxy)‐6‐(1H‐imidazol‐1‐yl)pyridine with axial halides exhibit octahedral trans M(L)4X2 geometries, confirmed by X‐ray diffraction. They feature a discrete 1,6M7−1 topology, identified using ToposPro analysis.
David Ezenarro‐Salcedo, Daniela Fonseca‐López, Alexander Patiño‐Cubides, María C. Velasco‐Pareja, María F. Yasnot‐Acosta, Camilo Serrano‐Sterling, Ana Rodríguez, Mario A. Macías, Adrian L. Orjuela, Augusto Valderrama‐Aguirre, John J. Hurtado   +10 more
wiley   +1 more source

Bronchial and Systemic Relationships of <i>Haemophilus</i> in Chronic Obstructive Pulmonary Disease. [PDF]

Int J Mol Sci
Monsó E, Casadevall C, Quero S, Pascual-Guàrdia S, Enríquez-Rodríguez CJ, Millares L, Montón C, Faner R, Capilla S, Seijo LM, Castro-Acosta A, Alvarez-Martínez C, Sibila O, Peces-Barba G, Cosio BG, Agustí A, Gea J.   +16 more
europepmc   +1 more source

Kinetic Fingerprints as Mechanistic and Clinical Roadmaps Across KIT Activation States

ChemMedChem, Volume 21, Issue 11, 15 June 2026.
Kinetic profiling of 172 compounds across KIT conformations—including D816V—reveals kinetic fingerprints that predict efficacy, selectivity, resistance, and inhibitors’ ability to stabilize key regulatory elements. Far from a secondary metric, binding kinetics provide mechanistic insights beyond affinity, offering a powerful framework for rational drug
Ana Corrionero, Niall Prendiville, Tatiana Cazorla, Maria Baena‐Nuevo, Röhm Sandra, Emilio Camafeita, Stefan Knapp, Patricia Alfonso   +7 more
wiley   +1 more source

Case report: VA-ECMO as a bridge to collapse in carcinoid heart disease. [PDF]

Eur Heart J Case Rep
Alañón Hernández AA, Tobar Ruiz J, Gil Fernandez JF, García de Casasola Rodriguez J, Plaza Martín M.   +4 more
europepmc   +1 more source

Synthesis, Characterization, and Anti‐Plasmodium falciparum Activity of a New Copper(II) Complex Containing 2‐(Tert‐Butoxy)‐6‐(1H‐imidazol‐1‐yl)pyridine

ChemMedChem, Volume 21, Issue 11, 15 June 2026.
The graphical abstract illustrates the formation of a Cu(II) complex from azole‐based ligand, highlighting metal–ligand synergy. The resulting coordination compound acts as a bioactive entity against Plasmodium, where metal coordination enhances antiparasitic activity, outperforming the free ligand and demonstrating its potential as an antimalarial ...
Alexander Patiño‐Cubides, María Camila Velasco‐Pareja, Mario A. Macías, María F. Yasnot‐Acosta, Ana Rodriguez, Augusto Valderrama‐Aguirre, John J. Hurtado   +6 more
wiley   +1 more source

Clinical and immunovirological status in children, adolescents and young adults with early-life-acquired HIV: a Spanish multi-cohort analysis since 2020. [PDF]

J Antimicrob Chemother
Tarancon-Diez L, Lazaro-Martin B, Goicoechea-Martínez J, Domínguez-Romero R, Gómez Sirvent J, Garrote E, Minguell Domingo L, Cervantes-Hernández E, Gavilán C, Fortuny C, Bernardino JI, Diez C, Montero-Alonso M, Roca-Oporto C, Ocampo A, Jiménez AB, Rius N, López Segura N, Escosa-García L, Prieto L, Ramos JT, Navarro-Gomez ML.   +21 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source