CONFLICTO DE INTERESES EN LA INVESTIGACIÓN BIOMÉDICA
Sofía P Salas
doaj
Digital speech‐based markers to advance prognosis in Alzheimer's disease
Abstract Validated prognostic tools are essential to advance drug development and clinical care in Alzheimer's disease, particularly as the field shifts toward the prevention of cognitive decline. While progress has been made in developing blood‐based biomarkers for the early detection of amyloid pathology, amyloid positivity alone does not reliably ...
Melissa Lee +6 more
wiley +1 more source
The interplay between osteosarcopenia and intrinsic capacity: insights and associations with all-cause mortality in the Toledo Study for Healthy Aging. [PDF]
Baltasar-Fernandez I +36 more
europepmc +1 more source
Abstract Patients with atypical variants of Alzheimer's disease (AD) often present at a younger age with predominantly non‐amnestic impairments and a more aggressive disease course. Historically, individuals with atypical presentations have not been included in large‐scale clinical trials, which typically focus on late‐onset, sporadic amnestic ...
Nick Corriveau‐Lecavalier +36 more
wiley +1 more source
Randomized double-blind clinical trial evaluating the effectiveness and safety of secondary prophylaxis with oral vancomycin versus placebo in the prevention of recurrence of <i>clostridioides difficile</i> infection in patients receiving systemic antibiotic therapy (PREVAN trial). [PDF]
San-Juan R +16 more
europepmc +1 more source
Abstract INTRODUCTION Adverse social conditions across the life course influence brain aging and dementia, yet their compounded impact on clinical phenotypes remains underexplored, particularly in Latin America, where social inequality and dementia burden are high.
Temitope Farombi +36 more
wiley +1 more source
Objective To characterize Fc‐glycosylation profiles in patients with anti‐N‐methyl‐D‐aspartate receptor encephalitis (NMDARe) and assess their association with antibody compartmentalization (cerebrospinal fluid [CSF] vs serum), disease triggers (viral, tumor‐related or idiopathic), and 1‐year outcomes.
Laura Marmolejo +16 more
wiley +1 more source
Helicobacter pylori Eradication Primary Care First-Line Prescriptions: Data From 200,000 Patients in a Real-World Cohort. [PDF]
Fernández-Antón E +6 more
europepmc +1 more source
Dry Deposition Strategies for MALDI–MS Imaging: Principles, Advances and Emerging Applications
ABSTRACT Matrix‐assisted laser desorption/ionisation mass spectrometry imaging (MALDI–MSI) has become a pivotal tool in biomedical research, enabling untargeted, spatially resolved analysis of molecular species in complex biological tissues. Among the critical steps in MALDI–MSI workflows, matrix deposition significantly influences sensitivity, spatial
Toufik Mahamdi, Oscar Yanes
wiley +1 more source
Impact of seasonal temperature variations on adverse outcomes in atrial fibrillation: comparative insights from Vigo and Murcia cohorts. [PDF]
Soler-Espejo E +8 more
europepmc +1 more source

