Results 221 to 230 of about 54,072 (237)
Studying When to Add Biological Therapy to Cytotoxic Therapy in Advanced Cancer Care Using Real World Data: How to Avoid Design Choices That Generate Immortal Time
Cancer Medicine, Volume 15, Issue 6, June 2026.ABSTRACT Background
Since real‐world data lack information on treatment assignment (usually the only information available is treatment prescription/administration) and early outcomes can happen in advanced cancer, some design choices may introduce immortal time due to selection or due to treatment strategy misclassification.Xabier Garcia‐Albeniz, Julia Vila‐Guilera, Manuel Zamparini, Helena Oliveres, Vicente Alonso‐Orduna, Jaime Feliu, Ana Fernández‐Montes, Marta Martín‐Richard, Elisa Gálvez‐Munoz, Ana Ruiz‐Casado, Alfonso Yubero‐Esteban, Jorge Aparicio, Julia Alcaide‐Garcia, Javier Gallego Plazas, Carlos Fernandez‐Martos, Rosa Gallego‐Sanchez, Mónica Guillot Morales, Rubén Leno, Francis Esposito, Sandra Lopez‐Prades, Míriam Cuatrecasas, Barbra A. Dickerman, Joan Maurel +22 morewiley +1 more sourceAllergen Immunotherapy for the Treatment of Eosinophilic Esophagitis. An EAACI Task Force Systematic Review
Clinical and Translational Allergy, Volume 16, Issue 6, June 2026.ABSTRACT Background
Multiple routes of allergen immunotherapy (AIT) are approved for several IgE‐mediated allergic diseases; however, the use of AIT in eosinophilic esophagitis (EoE) remains controversial and is supported by limited evidence. This review, conducted within the frame of an EAACI Task Force, aims to systematically evaluate the use of AIT ...Martina Votto, Georgios Rentzos, Darío Antolin‐Amerigo, Barbara Rymarczyk, George N. Konstantinou, Adam T. Fox, Antonella Cianferoni, Arzu Bakirtas, Carlo Maria Rossi, Marina Tsoumani, Enrico Heffler, Ingrid Terreehorst, Evangelia C. Apostolidou, Maria Beatrice Biló, Oliver Pfaar, Alfredo J. Lucendo, Georgios K. Nikolopoulos, Constantinos Pitsios +17 morewiley +1 more sourceHidradenitis suppurativa in patients with inflammatory bowel disease: a national multicenter study from the GETECCU-ENEIDA Registry. [PDF]
Ther Adv GastroenterolMadero-Velázquez L, de Francisco R, Herreros B, Yagüe C, Bujanda L, Calvet X, Ponferrada A, Aguas M, Rodríguez-Moranta F, Marín-Jiménez I, Catalá L, Gargallo-Pueyo C, Huguet J, Mesonero F, Monfort D, Sierra-Ausín M, Igualada L, Ricart-Gomez E, González-Vivo M, García MJ, Camba AH, Elorza A, Zabalza-San Martín L, Ramos L, Martín-Arranz MD, Ruiz-Núñez I, Martínez-Montiel P, Soto P, Roig C, Molina M, Mañosa M, Alba C, Barreiro-de Acosta M, Gisbert JP, Ramírez de la Piscina P, Lorente R, Zabana Y, Botella B, Riestra S, Belen-Galipienso O, Busquets D, Argüelles F, Pascual JC, Zapater P, Domènech E, Gutiérrez A. +45 moreeuropepmc +1 more sourceStandardized Pipeline for Metabolism and Cognition in GO‐DS21 Mouse Model: Investigating Down Syndrome Comorbidities
Current Protocols, Volume 6, Issue 6, June 2026.Abstract
Down syndrome (DS) is the most prevalent form of intellectual disability (ID) globally, with an incidence rate of approximately 1 in 1000 births, affecting over 5 million individuals worldwide. DS is characterized by a genetic profile that predisposes individuals to a range of medical and cognitive conditions, including ID and obesity, which ...Mohammed Selloum, Patricia da Silva‐Buttkus, Fabrice Riet, Nathalia R. V. Dragano, Lillian Garrett, Hugues Jacobs, Sabine M. Hölter, Nicolas Torquet, Birgit Rathkolb, Loic Lindner, Valerie Gailus‐Durner, Guillaume Pavlovic, Li Chan, Johannes Beckers, Benoit Petit Demoulière, Helmut Fuchs, Elodie Ey, Tania Sorg, Martin Hrabe de Angelis, Yann Herault, the GO‐DS21 Consortium +20 morewiley +1 more sourceA Novel Minimally Invasive Porcine Model of Functional Tricuspid Regurgitation. [PDF]
J Cardiovasc Dev DisGonzález-Cucharero C, Hernández I, Díez-Mata J, Ramírez-Carracedo R, Saura M, Baéz-Díaz C, Vázquez-López F, Sánchez-Margallo FM, Zamorano JL, Crisóstomo V, Zaragoza C. +10 moreeuropepmc +1 more sourceEffectiveness and safety of cenobamate after conversion to monotherapy or dual therapy in real‐world clinical practice
Epileptic Disorders, Volume 28, Issue 3, Page 775-785, June 2026.Abstract Objective
Patients with drug‐resistant epilepsy (DRE) typically take multiple anti‐seizure medications (ASMs) and are at risk of treatment‐related adverse events (AEs). This study assessed the impact of cenobamate monotherapy or dual therapy in patients with drug‐resistant epilepsy.Álvaro Sánchez‐Guijo Benavente, Guillermina García Martín, Estuardo Daniel Castro Ruiz, Pablo Cabezudo García, Yolanda López Moreno, José Carlos Estévez María, Irene Lorite Fuentes, Sergio Navarro Conti, Raquel Calle Calle, Alejandro Fernández Cabrera, Isabel Ros González, Dulce Campos Blanco, María Isabel Chamorro Muñoz, Pedro Jesús Serrano Castro +13 morewiley +1 more sourceA targeted combination therapy achieves effective pancreatic cancer regression and prevents tumor resistance. [PDF]
Proc Natl Acad Sci U S ALiaki V, Barrambana S, Kostopoulou M, Lechuga CG, Zamorano-Dominguez E, Acosta-Gallego D, Morales-Cacho L, Álvarez R, Sun P, Rosas-Perez B, Barrero R, Jiménez-Parrado S, López-García A, San Roman M, López-Gil JC, Drosten M, Sainz B, Musteanu M, Caleiras E, Dusetti N, Poli V, Sánchez-Bueno F, Guerra C, Barbacid M. +23 moreeuropepmc +1 more sourceCorrection: Delgado-Núñez et al. Isorhamnetin: A Nematocidal Flavonoid from <i>Prosopis laevigata</i> Leaves Against <i>Haemonchus contortus</i> Eggs and Larvae. <i>Biomolecules</i> 2020, <i>10</i>, 773. [PDF]
BiomoleculesDelgado-Núñez EJ, Zamilpa A, González-Cortazar M, Olmedo-Juárez A, Cardoso-Taketa A, Sánchez-Mendoza E, Tapia-Maruri D, Salinas-Sánchez DO, Mendoza-de Gives P. +8 moreeuropepmc +1 more source