Results 211 to 220 of about 743,546 (262)

Correction: Hypertension as predictive factor for bevacizumab-containing first-line therapy in metastatic breast and colorectal cancer in BRECOL (GEICAM/2011-04) study. [PDF]

Clin Transl Oncol
Rodríguez-Lescure Á, Gallego J, Garcia-Alfonso P, Massuti B, Márquez R, Calvo L, Sánchez-Rovira P, Antón A, Chacón JI, Ciruelos E, Ponce JJ, Santaballa A, Valladares-Ayerbes M, Dueñas MR, Alonso V, Aparicio J, Encinas S, Robles L, Escudero MJ, Caballero R, Bezares S, García-Ortiz MV, Morales-Ruiz T, de la Haba-Rodriguez J.   +23 more
europepmc   +1 more source

The Calcium‐Binding Protein S100A10 (p11) Is Required for Normal Motor Performance by Regulating Vesicle Dynamics at Excitatory Synapses

Acta Physiologica, Volume 242, Issue 2, February 2026.
ABSTRACT Aim Identifying interactors in sensorimotor processing and neurotransmission remains a current challenge for understanding neural information processing and brain function. Methods To evaluate the role of p11 in sensorimotor processing and excitatory synaptic neurotransmission, neuron‐specific lentivirus‐directed p11 silencing, small ...
Esther Vilches‐Herrando, Guillermo Rodríguez‐Bey, Rosendo G. Hernández, Ángela Gento‐Caro, Ángel M. Pastor, Antonio Campos‐Caro, David González‐Forero, Bernardo Moreno‐López   +7 more
wiley   +1 more source

Optochemical modulation of corneal cold nerve terminal impulse activity with a photochromic ion channel blocker

British Journal of Pharmacology, Volume 183, Issue 3, Page 545-559, February 2026.
Background and Purpose The functional organization of corneal cold nerve endings, critical structures in maintaining the ocular surface, remains poorly understood. Here, the photoisomerizable small‐molecule diethylamine‐azobenzene‐quaternary ammonium (DENAQ) was used to photomodulate activity of cold‐sensing nerve terminals in control and chronic tear ...
David Ares‐Suárez, Almudena Iñigo‐Portugués, Enrique Velasco, Susana Quirce, Fernando Aleixandre‐Carrera, Ariadna Díaz‐Tahoces, M. Carmen Acosta, Wan‐Chen Lin, Richard H. Kramer, Carlos Belmonte, Juana Gallar, Victor Meseguer   +11 more
wiley   +1 more source

Post-exposure prophylaxis with doxycycline (DoxyPEP) to prevent STIs in a real-world setting: the PRIDOX study. [PDF]

J Antimicrob Chemother
Palacios R, Gómez-Ayerbe C, Martín-Cortés S, González-Jiménez A, López-Jódar M, Pérez-Hernández IA, Santos J.   +6 more
europepmc   +1 more source

Increased levels of serum surfactant protein D are associated with cardiovascular disease incidence in the Spanish adult population: Di@bet.es study

European Journal of Clinical Investigation, Volume 56, Issue 2, February 2026.
Surfactant protein D (SP‐D), an innate immune system component, is associated with cardiovascular disease (CVD) events incidence in the Spanish adult general population. Higher SP‐D categories were linked to a greater risk of developing CVD, even among non‐smokers, despite increased SP‐D levels being traditionally related to smoking. The addition of SP‐
Wasima Oualla‐Bachiri, Ana Lago‐Sampedro, Eva García‐Escobar, Cristina Maldonado‐Araque, Elías Delgado, Felipe J. Chaves, Luis Castaño, Alfonso Calle‐Pascual, Josep Franch‐Nadal, Gabriel Olveira, Gemma Rojo‐Martínez, Viyey Doulatram‐Gamgaram, Sergio Valdés   +12 more
wiley   +1 more source

Novel insights into Alzheimer's disease through the study of individuals with Down syndrome. [PDF]

Alzheimers Dement
Head E, Cohen A, Fortea J, McGlinchey E.
europepmc   +1 more source

Serum sTREM2 Levels and Disability Progression in Patients With Primary Progressive Multiple Sclerosis

European Journal of Neurology, Volume 33, Issue 2, February 2026.
ABSTRACT Background Triggering receptor expressed on myeloid cells 2 (TREM2) is a microglia surface receptor that aids in tissue repair and debris clearance. The soluble form, sTREM2, found in both blood and cerebrospinal fluid, is considered a biomarker for microglial activation.
Nicolás Fissolo, Pascal Benkert, Andreu Vilaseca‐Jolonch, Yolanda Blanco, Harald Hegen, Klaus Berek, Francisco Pérez‐Miralles, Konrad Rejdak, Luisa Villar, Enric Monreal, Roberto Alvarez‐Lafuente, Franziska Bachhuber, Hayrettin Tumani, Sergio Martínez‐Yelamos, Antonio Sánchez‐López, Antonio García‐Merino, Lucía Gutiérrez, Tamara Castillo‐Triviño, Jan Lycke, Igal Rosenstein, Nieves Téllez, Roberto Furlan, Jan D. Lünemann, Michael Khalil, Jens Kuhle, Xavier Montalban, Manuel Comabella   +26 more
wiley   +1 more source

Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory

Immunology, Volume 177, Issue 2, Page 254-269, February 2026.
We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow‐derived innate cells, extensive transcriptomic analysis of haematopoietic progenitors, and challenge models of spirochetal infection, nonspecific inflammation, and model antigen ...
Samuel T. Pasco, Itziar Martín‐Ruiz, Sarai Araujo‐Aris, Diego Barriales, Janire Castelo, Leire Egia‐Mendikute, Monika Gonzalez, Jose Ezequiel Martin, Elena Molina, Maitane Mugica, Ainhoa Palacios, Iratxe Seoane, Naiara Gutiez, Estibaliz Atondo, Eneko Santos Fernández, Maddi Oyanguren, Borja Jimenez‐Lasheras, Ainize Peña‐Cearra, Ana M. Aransay, Asis Palazon, Aize Pellón, Leticia Abecia, Hector Rodriguez, Natalia Elguezabal, Juan Anguita   +24 more
wiley   +1 more source