Results 61 to 70 of about 4,071,660 (220)

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications

open access: yesArthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó   +84 more
wiley   +1 more source

Ética en la Investigación Biomédica

open access: yesRevista Internacional de Salud Materno Fetal, 2018
Debido al avance de la ciencia, las normas éticas han ido evolucionado, debido a excesos ocurridos en la historia, las normas éticas más aceptadas son la Declaración de Helsinki, Código de Núremberg, Reporte Belmont y las Pautas Éticas Internacionales ...
Yorsika Vargas Vargas   +6 more
doaj  

Long‐acting cabotegravir and rilpivirine in people with HIV receiving chronic anticoagulation: A real‐world case series

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background Long‐acting intramuscular cabotegravir plus rilpivirine (LA‐CAB + RPV) is an effective maintenance antiretroviral regimen for virologically suppressed people with HIV. However, its use in individuals receiving chronic anticoagulation is limited by concerns regarding intramuscular bleeding risk, and real‐world data are scarce.
Montserrat Laguno   +13 more
wiley   +1 more source

Crónica Congreso Internacional Investigación Biomédica

open access: yesBioderecho.es, 2015
Crónica ...
Salvador Tomás Tomás
doaj  

Metabolomic profiling of human lung tumor tissues – nucleotide metabolism as a candidate for therapeutic interventions and biomarkers

open access: yesMolecular Oncology, 2018
Although metabolomics has attracted considerable attention in the field of lung cancer (LC) detection and management, only a very limited number of works have applied it to tissues.
Paula Moreno   +9 more
doaj   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza   +12 more
wiley   +1 more source

Final 2‐Year Results of the REFORM Study: A Randomized Trial of Biolimus DCB Versus Paclitaxel DCB for In‐Stent Restenosis

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background In the REFORM trial, treatment of coronary in‐stent restenosis with a Biolimus A9™ drug‐coated balloon (BCB) was found to be inferior with respect to in‐segment percentage stenosis at 6‐months in comparison to treatment with a standard paclitaxel coated paclitaxel‐coated balloon (PCB). Aims In this manuscript, the final prespecified
Daniel O'Callaghan   +18 more
wiley   +1 more source

Substituent‐Dependent SERS Kinetics of Citrate‐Stabilized Gold Nanoparticles: Balancing Hotspot Formation and Colloidal Flocculation

open access: yesChemistry – A European Journal, EarlyView.
Reporter chemistry controls the operational window of liquid‐phase SERS. Para‐substituted benzenethiols induce distinct AuNPs colloidal regimes, ranging from delayed but stable hotspot formation to rapid flocculation‐dominated signal decay. The balance between SERS‐active‐state formation and colloidal loss defines whether a reporter provides reliable ...
Irene Calderon Gonzalez   +2 more
wiley   +1 more source

Respuesta sanitaria e investigación biomédica como respuesta a la pandemia COVID-19

open access: yes, 2021
La crisis sanitaria provocada por la enfermedad COVID-19 ha puesto a prueba nuestro sistema sanitario haciéndonos conscientes de una vulnerabilidad no esperable.
González Rojano, Esperanza   +3 more
core   +1 more source

N‐Sulfonyl Azalevoglucosan: A Versatile Platform for the Synthesis of Polysubstituted Piperidines

open access: yesChemistry – A European Journal, EarlyView.
Gain by strain: The synthesis of a levoglucosan analog, in which the pyranose oxygen has been replaced by a nitrogen, allows navigation on the piperidine ring to iteratively install functional groups at C1, C2, C3, C4, and C6 positions using simple experimental protocols with minimal protecting group manipulation.
Dylan Yorga   +6 more
wiley   +1 more source

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