Results 41 to 50 of about 110,805 (249)

CIBER-CLAP (CIBERCV Cardioprotection Large Animal Platform): A multicenter preclinical network for testing reproducibility in cardiovascular interventions

open access: yesScientific Reports, 2019
Despite many cardioprotective interventions have shown to protect the heart against ischemia/reperfusion injury in the experimental setting, only few of them have succeeded in translating their findings into positive proof-of-concept clinical trials ...
Xavier Rossello   +15 more
doaj   +1 more source

La libertad de creación y producción científica : especial referencia a la ley de investigación biomédica

open access: yesRevista de Derecho Político, 2009
No hay en la Constitución española una referencia directa y explícita a la investigación biomédica ni encontramos tampoco en el Texto Fundamental referencias a otros problemas derivados de estas nuevas tecnologías.
Yolanda Gómez Sanchez
doaj   +1 more source

Positive psychological profiles based on perceived health clustering in patients with cardiovascular disease: a longitudinal study

open access: yesBMJ Open, 2021
Objectives Psychological well-being and sociodemographic factors have been associated with cardiovascular health. Positive psychological well-being research is limited in the literature; as such, this study aimed to investigate how patients with ...
Rosario Castillo-Mayén   +8 more
doaj   +1 more source

Galanin receptor 2 modifies neuropeptide Y Y1 receptor internalization and β-Arrestin recruitment [PDF]

open access: yes, 2015
We have recently described a Galanin receptor 2(GALR2) and Neuropeptide Y Y1 receptor(NPYY1R) interaction at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers.
Borroto-Escuela, Dasiel   +8 more
core  

CSF‐Compartmentalized Antibody Glycoprofiles in NMDAR Encephalitis Associate with Etiology and Functional Recovery

open access: yesAnnals of Neurology, EarlyView.
Objective To characterize Fc‐glycosylation profiles in patients with anti‐N‐methyl‐D‐aspartate receptor encephalitis (NMDARe) and assess their association with antibody compartmentalization (cerebrospinal fluid [CSF] vs serum), disease triggers (viral, tumor‐related or idiopathic), and 1‐year outcomes.
Laura Marmolejo   +16 more
wiley   +1 more source

Investigación biomédica, intereses económicos y divulgación periodística

open access: yesRevista Latinoamericana de Bioética, 2017
Este artículo pretende afirmar que toda investigación, especialmente la biomédica, para que sea precisamente tal, tiene que poseer una dimensión ética.
Roberto Germán Zurriaráin
doaj  

Relapses, Comorbidities, and Predictors of Outcome in Anti‐GABAA Receptor Encephalitis

open access: yesAnnals of Neurology, EarlyView.
Objectives To characterize the magnetic resonance imaging (MRI) lesion dynamics, comorbidities, predictors of relapse, and outcomes in anti‐γ‐aminobutyric acid type A receptor (GABAAR) encephalitis, and assess the utility of LIM‐domain‐only‐protein 5 (LMO5) antibodies as tumor markers.
Claudia Papi   +33 more
wiley   +1 more source

La investigación biomédica y conductual en prisiones. Claves para un cambio de marco normativo

open access: yesRevista de Bioética y Derecho, 2021
La investigación biomédica y conductual si bien se erige en una actividad fundamental de cara al desarrollo científico en áreas básicas para el bienestar de la humanidad, constituye una temática que plantea cuestiones éticas de calado, en particular ...
Asier Urruela Mora
doaj   +1 more source

Liberación de sustancias en células senescentes [PDF]

open access: yes, 2014
La invención trata de nanodispositivos para la liberación controlada de sustancias que comprenden un soporte recubierto por oligosacáridos, donde dichos oligosacáridos comprenden al menos 3 unidades de monosacáridos, y donde al menos uno de los ...
Agostini, Alessandro   +9 more
core  

Three‐dimensional geometric morphometric analysis of diaphragmatic dome motion in COPD patients

open access: yesThe Anatomical Record, EarlyView.
Abstract Diaphragmatic dysfunction is a hallmark of chronic obstructive pulmonary disease (COPD), especially in emphysema, where hyperinflation alters diaphragm geometry and impairs inspiratory mechanics. However, quantitative three‐dimensional (3D) assessments of diaphragmatic dome shape and motion across COPD phenotypes are limited.
José M. López‐Rey   +5 more
wiley   +1 more source

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