Results 51 to 60 of about 110,805 (249)
Role of the LPA1 receptor in mood and emotional regulation [PDF]
, 2015 Depression is a debilitating psychiatric condition characterized by anhedonia and behavioural despair among others symptoms. Despite the high prevalence and devastating impact of depression, underlying neurobiological mechanisms of mood disorders are ...
Castilla-Ortega, Estela +8 more
core
Arthritis &Rheumatology, EarlyView.Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó +84 more
wiley +1 more source
Bioderecho.es, 2015 La investigación biomédica tiene como finalidad contribuir a la mejora de la salud y de la vida de las personas. La Constitución española manda proteger la salud de los ciudadanos.
Cecilia Gómez-Salvago Sánchez
doaj
Reduction of adult hippocampal neurogenesis modifies brain functional connectivity and enhances cocaine-seeking in mice [PDF]
, 2015 Recently, adult hippocampal neurogenesis has been proposed as a putative neuroplastic mechanism involved in those behavioural processes. In this work, we studied the effect of the inhibition of adult hippocampal neurogenesis using the DNA alkylating ...
Blanco, Eduardo +8 more
core
ESC Heart Failure, Volume 12, Issue 2, Page 1194-1202, April 2025.Abstract Aims Cardiac decompensation in cardiorenal syndrome (CRS) results in systemic congestion usually treated with diuretics. When despite high doses of diuretics, response is poor, ultrafiltration (UF) appears to be a useful and safe technique.
Borja Guerrero Cervera +12 more
wiley +1 more source
Antidepressant-like effects induced by galanin 2/neuropeptide Y Y1 heterodimers in the dentate gyrus of the hippocampus [PDF]
, 2017 Previously, we have described the Galanin (GAL) and Neuropeptide Y Y1 (NPYY1) interactions through GAL receptor 2 and NPYY1 receptor 1 (GALR2/NPYY1R) heterodimers in the Dentate Gyrus (DG) of the Hippocampus, using autoradiographic, in situ ...
Borroto-Escuela, Dasiel +8 more
core
Treated incidence of psychotic disorders in the multinational EU-GEI study [PDF]
, 2018 Jongsma, H.E., Gayer-Anderson, C., Lasalvia, A., Quattrone, D., Mulè, A., Szöke, A., Selten, J.-P., Turner, C., Arango, C., Tarricone, I., Berardi, D., Tortelli, A., Llorca, P.-M., De Haan, L., Bobes, J., Bernardo, M., Sanjuán, J., Santos, J.L., Arrojo ...
Bobes, Julio +4 more
core +1 more source
Epileptic Disorders, EarlyView.Abstract Objective Patients with drug‐resistant epilepsy (DRE) typically take multiple anti‐seizure medications (ASMs) and are at risk of treatment‐related adverse events (AEs). This study assessed the impact of cenobamate monotherapy or dual therapy in patients with drug‐resistant epilepsy.
Álvaro Sánchez‐Guijo Benavente +13 more
wiley +1 more source
La investigación biomédica en España (II). Evaluación del Fondo de Investigación Sanitaria (FIS) a través de los proyectos de investigación financiados en el período 1988-1995 a centros de investigación, facultades y escuelas [PDF]
, 1983 En un trabajo previo, publicado en esta misma revista, los autores han estudiado los resultados generados por los proyectos de investigación financiados por el Fondo de Investigación Sanitaria (FIS) a las Instituciones Sanitarias Asistenciales ...
de Abajo, Francisco J. +19 more
core +7 more sources
Ética en la Investigación Biomédica
Revista Internacional de Salud Materno Fetal, 2018 Debido al avance de la ciencia, las normas éticas han ido evolucionado, debido a excesos ocurridos en la historia, las normas éticas más aceptadas son la Declaración de Helsinki, Código de Núremberg, Reporte Belmont y las Pautas Éticas Internacionales ...
Yorsika Vargas Vargas +6 more
doaj