Results 31 to 40 of about 110,805 (249)

The object and the subject in scientific research

open access: yesMedisur, 2022
This article presents the dialectical unity between the object of study and the research subjects. Because usually, through the universe and the research sample, the subjects to be studied are declared, this work emphasizes the need to explicitly declare
Luis Alberto Corona Martínez   +2 more
doaj  

Adaptación cultural al español y validación psicométrica del Summary of Diabetes Self-Care Activities measure (SDSCA) en personas con diabetes mellitus tipo 2

open access: yesAtención Primaria, 2016
Objetivo: Llevar a cabo la adaptación cultural y la validación psicométrica del Summary of Diabetes Self-Care measure (SDSCA) en población española con diabetes mellitus tipo 2. Diseño: Estudio de validación clinimétrica.
Jorge Caro-Bautista   +5 more
doaj   +1 more source

Enhanced NETosis generation in radiographic axial spondyloarthritis: utility as biomarker for disease activity and anti-TNF-α therapy effectiveness

open access: yesJournal of Biomedical Science, 2020
Background Radiographic axial spondyloarthritis (r-axSpA) is a chronic inflammatory form of arthritis in which tumor necrosis factor (TNF)-α, a potent inducer of inflammatory response and a key regulator of innate immunity and of Th1 immune responses ...
Patricia Ruiz-Limon   +14 more
doaj   +1 more source

Counterintuitive Fluorescence Blue Shift in Symmetry Breaking Dicationic Bis(indolium) with Two‐Photon Absorption Properties for NIR Living Cell Imaging

open access: yesAdvanced Materials, EarlyView.
Highly water‐soluble dicationic bis(indolium) dyes have been prepared, showing excellent two‐photon absorption and light emission. Their fluorescence behavior discloses an unusual increasing blue shift with increasing solvent polarity, which, in parallel, is beneficial for enhanced detection in biological media.
Carlos Benitez‐Martin   +5 more
wiley   +1 more source

A Systematic Review on the Association between Schizophrenia and Bipolar Disorder with Chronic Obstructive Pulmonary Disease

open access: yesCOPD, 2023
A systematic review aimed to investigate the association between schizophrenia and bipolar disorder and chronic obstructive pulmonary disease (COPD), its prevalence and incidence, potential factors associated with its occurrence and its impact on ...
María José Jaén-Moreno   +5 more
doaj   +1 more source

Rehabilitación robótica en espasticidad de mano y muñeca

open access: yesRevista Colombiana de Medicina Física y Rehabilitación, 2021
Introducción. El presente estudio es una serie de casos clínicos que describe los resultados en el tratamiento de la espasticidad de mano y muñeca mediante órtesis robóticas realizado por el grupo de investigación F-Ciber-Rehabilitación en Manizales ...
José Fernando Gómez Rendón   +5 more
doaj   +1 more source

Bioética de la investigación biomédica con población mapuche [PDF]

open access: yes, 2011
Este trabajo presenta un análisis meta-etnográfico de las investigaciones biomédicas realizadas con población mapuche durante los años 1993 a 2003, con el objeto de examinar la pertinencia cultural de los aspectos éticos involucrados en el proceso de ...
Alarcón M., Ana María
core  

Bioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars

open access: yesAdvanced Materials, EarlyView.
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno   +15 more
wiley   +1 more source

Determinants of HDL Cholesterol Efflux Capacity after Virgin Olive Oil Ingestion: Interrelationships with Fluidity of HDL Monolayer [PDF]

open access: yes, 2018
Scope: Cholesterol efflux capacity of HDL (CEC) is inversely associated with cardiovascular risk. HDL composition, fluidity, oxidation, and size are related with CEC.
Castañer, Olga   +11 more
core   +2 more sources

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

open access: yesAdvanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda   +8 more
wiley   +1 more source

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