Results 121 to 130 of about 11,943,427 (291)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Accident investigation [PDF]

open access: yes
The National Transportation Safety Board (NTSB) has attributed wind shear as a cause or contributing factor in 15 accidents involving transport-categroy airplanes since 1970. Nine of these were nonfatal; but the other six accounted for 440 lives. Five of
Laynor, William G. Bud
core   +1 more source

Numerical investigation of boiling [PDF]

open access: yes, 2012
In this work, we study different phenomena that occur during nucleate boiling. We numerically investigate boiling using two phase flow direct numerical simulation based on a level set / Ghost Fluid method.
Colin, Catherine   +2 more
core  

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Investigation of spacecraft coatings [PDF]

open access: yes, 1969
Literature review provides compilation of properties of coating materials used for external application on space vehicles.

core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Enquêter sur nos attachements. Comment hériter de William James ?

open access: yesSociologies, 2015
This paper aims neither to assimilate pragmatism into the social sciences, nor to claim that the two are totally divergent: it merely raises the question of the social survey.
Antoine Hennion
doaj  

Effective investigative interviewing: Turning interrogations into conversations [PDF]

open access: yesNBP: Nauka, bezbednost, policija, 2017
An interrogation is essentially combative and high pressure, and therefore most often a negatively charged monologue of an interrogator trying to work a confession out of a subject.
Grossman Stephen
doaj  

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