Fall prevention through a systems approach: SEIPS, AcciMap and HTA findings from patient safety specialists. [PDF]
Age AgeingFray M, Jun GT, Hignett S.
europepmc +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Improving Interviews with Children in Abuse Cases: Current Perspectives from Police and Forensic Interviewers. [PDF]
Behav Sci (Basel)Morlat PV, Alison L.
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Reporting maternal deaths in Anglophone West Africa: A media content analysis of articles published online between 2015 and 2025. [PDF]
PLOS Glob Public HealthRoy K, Balogun N, Banke-Thomas A.
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
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Veterinarians' perspectives on animal welfare, legal enforcement, and forensic readiness in companion animal cruelty investigations in Thailand: A cross-sectional qualitative study. [PDF]
Vet WorldLorsirigool A +8 more
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The Independent Counsel Investigation, the Impeachment Proceedings, and President Clinton\u27s Defense: Inquiries into the Role and Responsibilities of Lawyers, Symposium, Proportionality as an Ethical Precept for Prosecutors in Their Investigative Role [PDF]
, 1999 Little, Rory K.
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source