Results 101 to 110 of about 658,410 (316)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
[Title supplied by cataloger]Young Investigator Adrian Salic at Experimental Biology ...
Unknown
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CRIME PREVENTION FUNCTION IN THE INVESTIGATION OF CRIMINAL CASES INVOLVING MINORS
The article refers to the prevention of crimes committed by minors as the main focus when prosecuting them. The current criminal legislation on minors (Article 20 of the Criminal Code of the Russian Federation) is analyzed.
KHALIKOV Aslyam Nailevich
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
VPRS 19767 Official Correspondence of the Office of the Special Investigator
<p style="margin:0cm 0cm 8pt">This series consists of the official correspondence of the Office of the Special Investigator (OSI) (VA 5326). <br /> <br /> The correspondence in this series is between the Special Investigator the ...
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Investigator Status in Criminal Proceedings
Bakalaura darba tēma ir „Izmeklētāja statuss kriminālprocesā”, kurā tiek apskatīts izmeklētāja statusa institūts un tā pilnvaru apjoms laika posmā no 1961.gada līdz šī brīža Latvijas Kriminālprocesa likumam.
Janševska, Imanta
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The United States medical and surgical journal.
Edited by George E. Shipman, 1865-1870."A quarterly magazine of the homœopathic practice of medicine and medical science in general."Mode of access: Internet.Merged with: The Medical investigator, to form: The United States medical ...
Shipman, George E. (George Elias), 1820-1893.
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