Results 121 to 130 of about 658,410 (316)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Investigating error in criminal proceedings
Хабаршы. Заң сериясы, 2016 In this paper, the author discussed some issues of improving the investigative practices, improve the quality of investigation of criminal cases, the rule of law in the activities of criminal prosecution and respect for the principles of the ...
Syrlybayev M.
doaj
Implementation of investigator-led drug clinical trial recruitment
Zhongguo linchuang yanjiuObjective Taking the implementation of recruitment for a drug clinical trial as an example, to discuss the implementation method of investigator-led recruitment for drug clinical trials from the perspective of the investigator’s organization, with a view
SONG Xia, KAN Tingting, ZHU Ling, CHEN Peiling, ZHANG Haitao
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
EFSUMB Young Investigator Award 2019
, 2019 The winner at EUROSON 2019 of the Young Investigator 3000 euro prize was Rogier R Wildeboer, The Netherlands for the abstract entitled : 3 D Multiparametric Ultrasound for Prostate Cancer ...
Mischi, Massimo +7 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Interactive Investigator, available through Virtual Museum Canada, is a website "for anyone with an interest in the different scientific methods used to solve crimes." Users will find a database of forensic science, containing short but ...
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Avaliação da estrutura genética da população atual de Santa Catarina com diferentes marcadores moleculares para aplicação na genética forense [PDF]
, 2014 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biologia Celular e do Desenvolvimento, Florianópolis, 2014A identificação genética humana está centrada na utilização de um conjunto de
Torres, Sandra Regina Rachadel
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