Results 141 to 150 of about 658,410 (316)

Mock Jurors\u27 Sensitivity to Investigator Bias

open access: yes, 2014
This study investigated jurors’ ability to identify investigator bias and determine if the camera angle at which lineup identifications were recorded impacted their ability to do so.
Carbery, Edwin F.
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Determinants of falsification of evidence in a criminal case and the results of operational-investigative activities in modern Russia

open access: yesИзвестия высших учебных заведений. Поволжский регион: Общественные науки
Background. Liability for falsification of evidence in a criminal case and the results of operational-search activities is provided for in Parts 2–4 of Article 303 of the Criminal Code of the Russian Federation.
A.V. Yashin
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

California Workers' Compensation SIU Investigator reference manual

open access: yes, 2009
Project (M.S., Criminal Justice) -- California State University, Sacramento, 2009.The purpose behind the creation of the California Workers??? Compensation Investigator Reference Manual is to compile important laws, regulations, websites and training ...
Wilson, Christine Diana
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Investigator in Criminal procedures

open access: yes, 2013
Bakalaura darba tēma „Izmeklētāja statuss kriminālprocesā”, ietver sevī vairākus būtiskus aspektus, piemēram, procesuālā statusa iegūšanas veidus, un problemātiku ar normatīvo regulējumu, kā arī izmeklētāja lomu un konstatējumu, ka izmeklētāju ...
Priekuls, Kaspars
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy