Results 81 to 90 of about 658,410 (316)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Rol del profesor en el proceso de enseñanza aprendizaje de la investigación en estudiantes de Enfermería de la Universidad de Antioquia, Colombia The teacher´s role in the learning process among nursing students at Universidad de Antioquia - Colombia

open access: yesInvestigación y Educación en Enfermería, 2008
Objetivo: describir el papel del profesor en el proceso de enseñanza aprendizaje de la investigación en el pregrado de enfermería de la Universidad de Antioquia, Colombia.
Beatriz Elena Ospina Rave   +2 more
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

IMPROVING THE CRIMINAL PROCEDURE MECHANISM OF THE INSTITUTE FOR SEARCHING FOR SUSPECTS IN CRIMES RELATED TO THE INVOLVEMENT OF RUSSIAN YOUNG PEOPLE IN TERRORIST AND EXTREMIST ORGANIZATIONS

open access: yesПравовое государство: теория и практика
One of the urgent issues in the detection of crimes related to the involvement of Russian young people in terrorist and extremist organizations and bringing perpetrators to criminal responsibility is the escape of suspects from preliminary ...
AZARENOK Nikolay Vasilyevich
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Perspectives on Research Internships for Medical Students and Young Doctors in Ghana: An Opportunity to Replenish the Stock of Physician Investigators?

open access: yesAdvances in Medical Education and Practice, 2020
Edem MA Tette,1 Ben A Gyan,2 Kwadwo A Koram3 1Department of Community Health, University of Ghana Medical School, Accra, Greater Accra Region, Ghana; 2Department of Immunology, Noguchi Memorial Institute for Medical Research University of Ghana, Accra ...
Tette EMA, Gyan BA, Koram KA
doaj  

Réflexions épistémologiques sur la constitution d’un corpus sociolinguistique. La relation d’enquête en question [PDF]

open access: yesRevue Roumaine d’Etudes Francophones, 2019
This work questions an important aspect of research in sociolinguistics that of the methodology of field surveys. The survey relationship is one of the most important elements in an experimental study in the humanities and social sciences. The purpose of
Souheila HEDID
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Investigator as the driver of the process

open access: yes, 2023
Izmeklētājs ir viena no svarīgākajām amatpersonām, kurai ir piešķirts pilnvarojums veikt nepieciešamās izmeklēšanas darbības pirmstiesas izmeklēšanas procesa gaitā.
Lukašova, Kristiāna
core  

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