Results 111 to 120 of about 19,007,438 (352)

Stress concentrations around voids in three dimensions : The roots of failure [PDF]

open access: yes, 2017
Funding This work forms part of a NERC New Investigator award for DH (NE/I001743/1), which is gratefully acknowledged. Acknowledgments The authors would like to acknowledge the reviewers, Elizabeth Ritz and Phillip Resor.
Bubeck, A.   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Rol del profesor en el proceso de enseñanza aprendizaje de la investigación en estudiantes de Enfermería de la Universidad de Antioquia, Colombia The teacher´s role in the learning process among nursing students at Universidad de Antioquia - Colombia

open access: yesInvestigación y Educación en Enfermería, 2008
Objetivo: describir el papel del profesor en el proceso de enseñanza aprendizaje de la investigación en el pregrado de enfermería de la Universidad de Antioquia, Colombia.
Beatriz Elena Ospina Rave   +2 more
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

IMPROVING THE CRIMINAL PROCEDURE MECHANISM OF THE INSTITUTE FOR SEARCHING FOR SUSPECTS IN CRIMES RELATED TO THE INVOLVEMENT OF RUSSIAN YOUNG PEOPLE IN TERRORIST AND EXTREMIST ORGANIZATIONS

open access: yesПравовое государство: теория и практика
One of the urgent issues in the detection of crimes related to the involvement of Russian young people in terrorist and extremist organizations and bringing perpetrators to criminal responsibility is the escape of suspects from preliminary ...
AZARENOK Nikolay Vasilyevich
doaj   +1 more source

Getting away with murder [PDF]

open access: yes, 2011
Where once children aspired to the science careers of astronauts, surgeons or vets, now the career of choice (apart from ‘celebrity’) is Crime Scene Investigator.
Herridge, Deborah
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Socioeconomic factors and COVID-19 mortality in immune-mediated rheumatic diseases patients: regional analysis from Argentina, Mexico and Brazil

open access: yesAdvances in Rheumatology
Background SARS-CoV-2 infection has become a major international issue, not only from a medical point of view, but also social, economic and political.
Marco Ulises Martinez-Martinez   +29 more
doaj   +1 more source

Perspectives on Research Internships for Medical Students and Young Doctors in Ghana: An Opportunity to Replenish the Stock of Physician Investigators?

open access: yesAdvances in Medical Education and Practice, 2020
Edem MA Tette,1 Ben A Gyan,2 Kwadwo A Koram3 1Department of Community Health, University of Ghana Medical School, Accra, Greater Accra Region, Ghana; 2Department of Immunology, Noguchi Memorial Institute for Medical Research University of Ghana, Accra ...
Tette EMA, Gyan BA, Koram KA
doaj  

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