Results 131 to 140 of about 135,456 (314)

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

An application of the Sakai's theorem to the characterization of H*-algebras

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1995
The well-known Sakai's theorem, which states that every derivation acting on a von Neumann algebra is inner, is ,used to obtain a new elegant proof of the Saworotnow's characterization theorem for associative H*-algebras via two-sided H*-algebras.
Borut Zalar
doaj   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Inverse problems for a nonlocal wave equation with an involution perturbation

open access: yes, 2016
Two inverse problems for the wave equation with involution are considered. Results on existence and uniqueness of solutions of these problems are presented. c (cid:13) 2016 All rights reserved.
M. Kirane, N. Al-Salti
semanticscholar   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Involutions on Baxter Objects [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2012
Baxter numbers are known to count several families of combinatorial objects, all of which come equipped with natural involutions. In this paper, we add a combinatorial family to the list, and show that the known bijections between these objects respect these involutions.
openaire   +5 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Cabergoline inhibits prolactin secretion and accelerates involution in dairy cows after dry-off.

open access: yesJournal of Dairy Science, 2016
Dairy cattle require a dry period between successive lactations to ensure optimal milk production. Because prolactin (PRL) is necessary for the initiation and maintenance of milk production, strategies that can inhibit PRL secretion might hasten the ...
M. Boutinaud   +13 more
semanticscholar   +1 more source

Refined restricted involutions

open access: yesEuropean Journal of Combinatorics, 2007
20 ...
Emeric Deutsch   +2 more
openaire   +3 more sources

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

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