Results 71 to 80 of about 629,447 (347)

Propidium iodide staining underestimates viability of adherent bacterial cells

open access: yesScientific Reports, 2018
Combining membrane impermeable DNA-binding stain propidium iodide (PI) with membrane-permeable DNA-binding counterstains is a widely used approach for bacterial viability staining.
Merilin Rosenberg   +2 more
semanticscholar   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Temperature Dependence of the Urbach Energy in Lead Iodide Perovskites.

open access: yesJournal of Physical Chemistry Letters, 2019
To gain insight into the properties of photovoltaic and light-emitting materials, detailed information about their optical absorption spectra is essential.
M. Ledinský   +8 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Crystal structure and Hirshfeld surface analysis of the salt 2-iodoethylammonium iodide – a possible side product upon synthesis of hybrid perovskites

open access: yesActa Crystallographica Section E: Crystallographic Communications
The title organic–inorganic hybrid salt, C2H7IN+·I−, is isotypic with its bromine analog, C2H7BrN+·Br− [Semenikhin et al. (2024). Acta Cryst. E80, 738–741]. Its asymmetric unit consists of one 2-iodoethylammonium cation and one iodide anion.
Hanna R. Petrosova   +4 more
doaj   +1 more source

Recovery of Iodine as Triiodide by Strongly Basic Anion Exchange Resins; Development of Chromatographic Method [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering
The present study outlines a general process to recover iodine from brine water or wastewater by strongly basic anion exchange resins. At first, iodide anions were oxidized to iodine or triiodide (the appropriate amount of H2O2 and HCl was added to the ...
Shahram Sharifnia, Mona Akbari
doaj   +1 more source

Quantification of propidium iodide delivery with millisecond electric pulses: A model study [PDF]

open access: yes, 2014
A model study of propidium iodide delivery with millisecond electric pulses is presented; this work is a companion of the experimental efforts by Sadik et al. [1].
Lin, Hao, Yu, Miao
core  

Iridium complexes bearing a PNP ligand, favoring facile C(sp^3)–H bond cleavage [PDF]

open access: yes, 2011
Hydrogen iodide is lost upon reaction of PNP with IrI_3, where PNP = 2,6-bis-(di-t-butylphosphinomethyl)pyridine to give crystallographically characterized Ir(PNP)*(I)_2, which reacts with H_2 to give Ir(PNP)(H)(I)_2.
Goddard, William A., III   +4 more
core   +1 more source

Understanding how excess lead iodide precursor improves halide perovskite solar cell performance

open access: yesNature Communications, 2018
The presence of excess lead iodide in halide perovskites has been key for surpassing 20% photon-to-power conversion efficiency. To achieve even higher power conversion efficiencies, it is important to understand the role of remnant lead iodide in these ...
Byung-Wook Park   +12 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

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