Results 91 to 100 of about 23,133 (214)

Actinomycin Derivatives: Structural Diversification and Biological Activities

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Özge Can, Erdal Bedir
wiley   +1 more source

Exploring the Chemical Space Around Protoflavonoids: Synthesis and Antitumor Activity of Protochalcones

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
Natural and synthetic protoflavonoids offer potent anticancer properties, but their chemical space remains largely unexplored. This study details the synthesis of eleven p‐hydroxydienone derivatives from chalcone precursors. We evaluated their antiproliferative effects across four human gynecological cancer cell lines.
Tímea Gonda   +7 more
wiley   +1 more source

Auto‐Click Synthesis of a Copper(I)–N‐Heterocyclic Carbene Porous Organic Polymer and Its Transmetalation to Palladium(II) for Azide–Alkyne Cycloaddition and Cross‐Coupling Reactions

open access: yesEuropean Journal of Inorganic Chemistry, Volume 29, Issue 23, 13 August 2026.
An azide‐functionalized Cu(I)–NHC complex acts as both a monomer and a catalyst in an auto‐click polymerization, yielding a Cu(I)–NHC polymer that can be transmetalated to Pd(II). The two materials catalyze copper‐catalyzed azide–alkyne cycloaddition, C–N/C–O coupling, and Suzuki–Miyaura reactions, while copper reloading restores activity.
Cyril Nicolay   +6 more
wiley   +1 more source

1‐(Acetylamino)thioxanthones and Derivatives: Synthesis From 1‐Halogenothioxanthones and Biological Properties

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 30, 12 August 2026.
The conversion of 1‐halogenothioxanthones into 1‐(acetylamino) derivatives and their NaH‐mediated cyclization have been optimized. This rapid method yields thiochromeno[4,3,2‐de]quinol‐2‐ones that exhibit promising in vitro anticancer activity. Institute and/or researcher Bluesky usernames: https://bsky.app/profile/iscr‐rennes.bsky.social.
Najet Ballagha   +12 more
wiley   +1 more source

PEROXIDAÇÃO EM AMOSTRAS DE MILHO, PROTEGIDAS OU NÃO POR ETOXIQUIM

open access: yesCiência Animal Brasileira, 2006
O objetivo deste experimento foi avaliar a eficiência do antioxidante etoxiquim, quando acrescido a amostras de milho triturado, armazenadas por diferentes períodos.
Marcos Antônio Anciuti   +6 more
doaj  

Pd‐Catalyzed Direct Access to 2‐Substituted (Aza)benzo[b]furans via Cascade Reactions Under “On‐Water” Conditions

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
An “on‐water” scalable Pd‐catalyzed heteroannulation delivers benzofurans and furopyridines at ultralow catalyst loadings (down to 0.005 mol%), providing products essentially free of palladium residues. In addition to a broad substrate scope (aryl, alkenyl, and alkyl alkynes with o‐iodophenols or 2‐iodo‐3‐hydroxypyridines), this protocol enables a new ...
Iratxe Astarloa   +3 more
wiley   +1 more source

Continuous Flow Photocatalytic Hydrogen‐Transfer Reduction of Benzaldehydes in a Helical Packed‐Bed Reactor

open access: yesChemCatChem, Volume 18, Issue 15, 14 August 2026.
Heterogeneous photocatalysis has attracted attention as a green alternative to thermal catalytic processes. However, continuous operation remains challenging due to mass‐transfer limitations and nonuniform light irradiation. Herein, we report a helical fixed‐bed photocatalytic flow reactor consisting of a FEP tube packed with TiO2‐coated zircon beads ...
Katsumi Tanimoto   +4 more
wiley   +1 more source

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