Results 111 to 120 of about 23,133 (214)

Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping

open access: yesThe Chemical Record, Volume 26, Issue 8, August 2026.
Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato   +3 more
wiley   +1 more source

Oxygen Attachment Dissociation of Protonated Reserpine and Its Analogs

open access: yesRapid Communications in Mass Spectrometry, Volume 40, Issue 14, 30 July 2026.
ABSTRACT Rationale Carbon–carbon double bonds are ubiquitous structural motifs in natural products and pose a key challenge in locating their presence in analytes via MS‐based methods. Here, we use the alkaloid reserpine as a model system to examine whether OAD reactions can locate quaternary double bonds embedded in fused multicyclic structures ...
Jack G. Li   +5 more
wiley   +1 more source

Sultams as Dual Inhibitors of Human Carbonic Anhydrase and Thioredoxin Reductase

open access: yesChemMedChem, Volume 21, Issue 14, 29 July 2026.
A series of sultam‐based N‐acyl derivatives with potential applications as dual TrxR1 and CA inhibitors were synthesized and evaluated. TrxR1 screening identified several active compounds, with inhibitory potency influenced by the type and orientation of substituents.
Aleksandrs Pustenko   +8 more
wiley   +1 more source

Acyclic Hydrocarbon α,ω‐Dienes: From Biomass and Plastic Upcycling to Carbocycles, Precision Polymers, and Cross‐Linked Elastomers

open access: yesChemSusChem, Volume 19, Issue 14, 29 July 2026.
Hydrocarbon α,ω‐dienes are mainly produced from steam‐cracking derivatives, but high costs, complexity, and environmental impact limit their use. This review highlights sustainable paths from biomass and plastic upcycling, and surveys catalytic transformations into carbocycles and specialty polymers, emphasizing their role as modular building blocks ...
Rosa Villaccio, Giuseppe Leone
wiley   +1 more source

Late‐Stage Functionalization of Peptides on the Solid Phase

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 31, 27 July 2026.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner   +2 more
wiley   +1 more source

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