Total plasma homocysteine measurement: Evaluation of the Abbott immunoassay, comparison with the JEOL ion exchange chromatography and investigation of its clinical utility [PDF]
Practical Laboratory Medicine, 2022 Objectives: Homocysteine is an intermediary amino acid formed in methionine metabolism, with elevated total homocysteine (tHCY) being a biomarker of cardiovascular and cerebrovascular diseases. We evaluated the Abbott ARCHITECT tHCY immunoassay, compared
Kai Fung Kevin Suen +6 more
doaj +2 more sources
Lentiviral Vector Purification Using Nanofiber Ion-Exchange Chromatography [PDF]
Molecular Therapy: Methods & Clinical Development, 2019 Lentiviral vectors (LVs) are used in cell and gene therapies due to their ability to transduce both dividing and non-dividing cells while carrying a relatively large genetic payload and providing long-term gene expression via gene integration.
Jelena Ruscic +4 more
doaj +2 more sources
Consecutive Affinity and Ion-Exchange Chromatography for AAV9 Vectors Purification [PDF]
BiomedicinesBackground: Irrespective of the rapid development of AAV-based gene therapy, the production of clinical-grade vectors has a bottleneck resulting from product-related impurities such as empty and partially filled capsids, which lack a functional ...
Ozgun Firat Duzenli, George Aslanidi
doaj +2 more sources
Water, electricity and ion exchange; how Hamish Small sustained the evolution of ion chromatography
Heliyon, 2021 Since the development of synthetic ion exchange resins in 1935, the electrochemical properties of these unique materials have intrigued researchers. In 1951, Hamish Small was introduced to synthetic ion exchange resin when he studied the electromigration
John M. Riviello
doaj +1 more source
Effect of ion-exchange chromatography on removal of fibronectin in von Willebrand factor
Zhongguo shuxue zazhi, 2023 Objective To study the removal effect of fibronectin(Fn) from von willebrand factor(vWF) by ion-exchange chromatography through processing human coagulation factor Ⅷ chromatographic washing products, in order to select a method that can effectively ...
Zheng ZHOU +4 more
doaj +1 more source
Journal of Chromatography Open, 2023 In recent decades, there has been a trend toward using larger biological molecules as new active pharmaceutical ingredients (APIs) instead of the classical small organic API molecules.
Torgny Fornstedt, Martin Enmark
doaj +1 more source
The Role of Vibrio cholerae Haemagglutinin Protease (HAP) in Extra-Intestinal Infection [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Based on the diversity of surface O antigen Vibrio cholerae can be classified into 206 serogroups. Vibrio cholerae is the causative agent of cholera and extra intestinal infections like, septicemia, wound infection and haemorrhagic ...
Amit Ghosh, Hemanta Koley, Amit Pal
doaj +1 more source
The role of lactic acid adsorption by ion exchange chromatography. [PDF]
PLoS ONE, 2010 BACKGROUND: The polyacrylic resin Amberlite IRA-67 is a promising adsorbent for lactic acid extraction from aqueous solution, but little systematic research has been devoted to the separation efficiency of lactic acid under different operating conditions.
Qiang Gao +7 more
doaj +1 more source
Hydrophobicity of polymer based anion-exchange columns for ion chromatography
Heliyon, 2021 The regularities of the retention of alkanoic and alkanesulfonic acids homologues were investigated for the set of 36 anion-exchange columns produced by various manufacturers.
Pavel N. Nesterenko +1 more
doaj +1 more source
Czech Journal of Food Sciences, 2011 An ion-exchange chromatography method with visible light detection was developed for the simultaneous determination of chloride, bromide, and iodide in foodstuffs.
Lingyun Yu +4 more
doaj +1 more source