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Model-based integrated optimization and evaluation of a multi-step ion exchange chromatography

Separation and Purification Technology, 2014
Thiemo C Huuk   +3 more
semanticscholar   +3 more sources

Ion-Exchange Chromatography

Analytical Chemistry, 1962
Chromatographic methods using either the synthetic ion-exchange resins or other ion-exchange materials are widely used for the separation of many classes of ionized or ionizable substances. Substances of both high and low molecular weight have been successfully chromatographed on ion-exchange materials.
Robert Kunin, F. X. McGarvey
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Ion-exchange chromatography

Analytical Chemistry, 1964
Ion-exchange chromatography is a versatile method of separation and concentration which is applicable to many kinds of analysis, inorganic, organic, and biochemical. The experimental technique is simple and in most cases fairly rapid. In the great majority of inorganic applications, all that is needed is a tube about 25 cm long and 1 cm i.d ...
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Chromatography of Proteins. I. Cellulose Ion-exchange Adsorbents

Journal of the American Chemical Society, 1956
E. A. Peterson, H. A. Sober
semanticscholar   +3 more sources

Ion-exchange chromatography

Analytica Chimica Acta, 1967
Abstract A review is given of variables which affect the separation factors in ion-exchange chromatography. In favorable cases the influence of complex formation, pH, and eluant concentration can be predicted by simple calculations, whereas the interaction forces inside the resin phase are still largely unexplored.
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Ion-Exchange Chromatography

1979
Ion exchangers consist of an insoluble framework (matrix) containing covalently bonded dissociable functional groups at accessible sites. These are either sulfonic acid groups or, less importantly, carboxyl groups in the case of cation exchangers, and tertiary amino or quaternary ammonium groups for anion exchangers.
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ION EXCHANGE CHROMATOGRAPHY OF THE FREE AMINO ACIDS IN THE PLASMA OF THE NEWBORN INFANT.

Pediatrics, 1965
1. A micromethod for the determination of amino acids by ion exchange chromatography was applied to the quantitative determination of the free amino acids in 0.1 ml of plasma of the newborn infant.
J. Dickinson, H. Rosenblum, P. Hamilton
semanticscholar   +1 more source

Antibody Purification: Ion-Exchange Chromatography

2009
Ion exchange chromatography techniques are the focus of this chapter and they showcase the power of this method for the purification of proteins and monoclonal antibodies. The technique is powerful and can separate biomolecules that have minor differences in their net charge, e.g., two protein molecules differing by a single charged amino acid.
Ana Cristina, Grodzki, Elsa, Berenstein
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Ion Exchange in Paper Chromatography

Nature, 1953
IT has been shown by Schute that several mixtures of alkaloids can be separated by chromatography on paper using aqueous ammonia1. Because the chromatograms have the characteristics of a partition chromatogram, it is probable that the above separation is due to partition between an aqueous imbibition phase and an aqueous mobile phase.
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