Abstract Purpose Stereotactic radiotherapy (SRT) is a highly effective treatment with precision for small, localized lesions. Proton therapy, characterized by the Bragg peak, offers superior dose conformity compared to photon‐based approaches. However, challenges remain in minimizing lateral penumbra and optimizing dose delivery, particularly for small
Chen‐Yu Chou+3 more
wiley +1 more source
Revisiting In-Gas Transformations of Quinate Conjugates Through the LC-qTOF-MS and Molecular Networking Topology. [PDF]
Moyo NB, Madala NE.
europepmc +1 more source
Radiotherapy medical physics in the Philippines: A contemporary overview
Abstract Purpose With cancer ranking as the third leading cause of death in the Philippines and a disparity in healthcare resources across regions, this research aimed to assess the state of radiotherapy medical physics in the country. Methodology The study utilized a comprehensive online survey with 94 structured questions answered by 19 clinics ...
John Paul C. Cabahug+4 more
wiley +1 more source
APCI-Multistage Mass Spectrometry Following Liquid Chromatography for Selected 4-Desmethyl-Sterols and Their Deuterium-Labelled Analogues Unveils Characteristic Fragmentation Routes for Cholesterol and Phytosterols Identification. [PDF]
Cinquepalmi V+4 more
europepmc +1 more source
An Analysis for IDH‐Mutant Grade 4 Astrocytoma Based on WHO CNS 5: Implication of Clinical Practice
ABSTRACT Purpose There is ongoing debate regarding the therapeutic approach and prognosis for IDH‐mutant grade 4 astrocytoma, a newly defined subtype of diffuse glioma in the 2021 WHO classification system for central nervous system tumors (WHO CNS 5). The aim of this study was to explore the clinical outcome and prognosticators for newly diagnosed IDH‐
Xianxin Qiu+13 more
wiley +1 more source
Suppression of mechanical hypersensitivity and change in the expression of the dopamine D2 receptor by administration of anti-CGRP antibody into the trigeminal ganglion in trigeminal neuropathic pain model rats. [PDF]
Maegawa H, Usami N, Kudo C, Niwa H.
europepmc +1 more source
Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp+8 more
wiley +1 more source
Construction of High-Performance Membranes for Vanadium Redox Flow Batteries: Challenges, Development, and Perspectives. [PDF]
Huynh TTK+5 more
europepmc +1 more source
Fast single metal cation conduction in ion-water aggregated aqueous battery electrolytes. [PDF]
Xu C+5 more
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio+11 more
wiley +1 more source