Results 101 to 110 of about 2,447,449 (300)

MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter

Communications Biology, 2018
Through a MicroED structure of NaK ion channel, Shian Liu and Tamir Gonen identify a process of dilation coupled with Na+ movement, providing mechanistic insights into ion conduction and gating.
Shian Liu, Tamir Gonen
doaj   +1 more source

Motifs in the permeation pathway of connexin channels mediate Ca2+ and voltage sensing.

Frontiers in Physiology, 2014
Connexin channels mediate electrical coupling, intercellular molecular signaling and extracellular release of signaling molecules. Connexin proteins assemble intracellularly as hexamers to form plasma membrane hemichannels.
Andrew L. Harris, Jorge E. Contreras
doaj   +1 more source

Structure‐Guided Balancing of Ambipolar Transport Enables Symmetric Switching in Heterojunction Bilayer Organic Transistor Inverters

Advanced Functional Materials, Volume 36, Issue 86, 26 October 2026.
Balancing the spatially separated p‐ and n‐type transport pathways in heterojunction‐bilayer OTFTs enables symmetric inverter switching (VM ≈ 0.5VDD), whereas discrete integration of unipolar OTFTs gives polarity‐dependent and resistive responses. ABSTRACT High inverter performance in ambipolar organic electronics requires balanced channel strengths ...
Sohyun Choi, Young Yong Kim, Ji Ho Youk, Hoichang Yang   +3 more
wiley   +1 more source

Stochastically gating ion channels enable patterned spike firing through activity-dependent modulation of spike probability.

PLoS Computational Biology, 2009
The transformation of synaptic input into patterns of spike output is a fundamental operation that is determined by the particular complement of ion channels that a neuron expresses.
Joshua T Dudman, Matthew F Nolan
doaj   +1 more source

An Adaptive Inhibitory WSe2 Transistor for Retinomorphic In‐Sensor Image Processing

Advanced Functional Materials, EarlyView.
Conventional retinomorphic devices typically require deliberate gate‐bias tuning for each illumination condition. In this paper, we demonstrate an adaptive inhibitory WSe2 transistor that uses photo‐induced regime shift between the subthreshold and accumulation modes to achieve decision‐free, intensity‐adaptive image processing within a single pixel ...
Juhwan Baek, Junhwa Oh, Hyeonjung Kim, Minsik Park, Haein Cho, Jin Young Park, Hyeonchang Son, Taeyun Kim, Sung‐Un An, Yamin Zhang, Hyeon‐Jin Shin, Seyong Oh, Dong‐Ho Kang   +12 more
wiley   +1 more source

Coupling ligand binding to ion channel gating in NMDA receptors [PDF]

, 2011
The NMDA receptor is a ligand-gated ion channel that mediates a fundamental component of excitatory synaptic transmission in the mammalian central nervous system.
Talukder, Iehab
core  

Self-organized enhancement of conductivity in biological ion channels [PDF]

, 2013
We discuss an example of self-organisation in a biological system. It arises from long-range ion-ion interactions, and it leads us to propose a novel mechanism of enhanced conduction in ion channels.
Kaufman, Igor, Khovanov, Igor A., McClintock, Peter V. E., Eisenberg, R. S., Luchinsky, Dmitrii G., Tindjong, Rodrigue   +5 more
core   +3 more sources

Genetically Programmed Shape‐Morphing of Engineered Living Materials

Advanced Functional Materials, EarlyView.
Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker, Yuchen Liu, Miguel Baños, Rosanne Schmachtenberg, Mahmudul Hasan, Claudia Fink‐Straube, Luai R. Khoury, Wilfried Weber   +7 more
wiley   +1 more source

FKBP12 activates the cardiac ryanodine receptor Ca2+-release channel and is antagonised by FKBP12.6 [PDF]

, 2012
Changes in FKBP12.6 binding to cardiac ryanodine receptors (RyR2) are implicated in mediating disturbances in Ca2+-homeostasis in heart failure but there is controversy over the functional effects of FKBP12.6 on RyR2 channel gating.
Mano Sitsapesan (182017), Tsaneva-Atanasova, Krasimira, Samantha J Pitt, Pitt Samantha J., Zaccai, N, Krasimira Tsaneva-Atanasova (144624), Sitsapesan, Rebecca, Tsaneva-Atanasova, KT, Pitt, SJ, Stephen O'Neill (182027), Zaccai Nathan R., Tsaneva-Atanasova Krasimira, Sitsapesan Rebecca, O'Neill Stephen, Galfre, Elena, Pitt, Samantha Jane, Nathan R. Zaccai (182021), Venturi Elisa, Sitsapesan, Mano, Mano Sitsapesan, Galfré Elena, Rebecca Sitsapesan (182033), Sitsapesan Mano, Rebecca Sitsapesan, Venturi, E, Samantha J. Pitt (182004), Stephen O'Neill, Elisa Venturi, Elena Galfré, Elena Galfré (182000), Elisa Venturi (182009), O'Neill, Stephen, Nathan R Zaccai, Sitsapesan, R, O'Neill, S, Krasimira Tsaneva-Atanasova, Venturi, Elisa, Zaccai, Nathan R, Sitsapesan, M, Pitt, Samantha Jane; id_orcid, Galfre, E   +40 more
core   +1 more source

Electrical Control of the Transduction Channels’ Gating Force in Mechanosensory Hair Cells

Advanced Science
The inner ear's hair cells rely on mechanosensitive ion channels to convert vibrations of their hair bundles into electrical signals. The mechanical correlates of channel gating—the gating force and the gating swing—are fundamental determinants of hair ...
Achille Joliot, Laure Stickel, Pascal Martin   +2 more
doaj   +1 more source