Results 81 to 90 of about 99,152 (293)

Stochastic models of ion channel gating

Scholarpedia, 2008
Stochastic models of ion channel gating date back as far as the pioneering work of Hodgkin and Huxley (1952), whose gating variables are often interpreted as probabilities. Sakmann and Neher directed the efforts that led to the first single-channel recordings, for which they won the Nobel Prize in Physiology and Medicine in 1991.
Tilman Kispersky, John A. White
openaire   +1 more source

Regiorandom Polythiophenes for Fully Stretchable Electrochemical Transistors and Logic Circuits

Advanced Functional Materials, EarlyView.
Regiorandom (RRa) polythiophenes, once regarded as unsuitable for electronics, exhibit exceptional switching performance via volumetric electrochemical doping. Optimized RRa‐based organic electrochemical transistors (OECTs) achieve a high on/off ratio (≈104), stable operation under 200% strain, and enable fully stretchable logic gates, demonstrating ...
Dong Hyun Park, Min Su Kim, Kyu Yeon Kim, Jae Hyun Han, Moon Sung Kang, Kyung Gook Cho, Keun Hyung Lee   +6 more
wiley   +1 more source

A Quantum-mechanical description of ion motion within the confining potentials of voltage gated ion channels

, 2012
Voltage gated channel proteins cooperate in the transmission of membrane potentials between nerve cells. With the recent progress in atomic-scaled biological chemistry it has now become established that these channel proteins provide highly correlated ...
Bernroider G., Bernroider G., Briegel H. J., Corry B., Gustav Bernroider, Johann Summhammer, Thomas J. W., Vahid Salari   +7 more
core   +2 more sources

Gating-induced large aqueous volumetric remodeling and aspartate tolerance in the voltage sensor domain of Shaker K+ channels [PDF]

, 2018
Indexación: Scopus.ACKNOWLEDGMENTS. We thank Chris Lingle and Yu Zhou (Washington University) for critical reading of the manuscript and Victoria Prado for Xenopus care and oocyte preparation.
Díaz-Franulic, I., González-Pérez, V., Moldenhauer, H., Naranjo, D., Navarro-Quezada, N.   +4 more
core   +1 more source

2D Magnetic and Topological Quantum Materials and Devices for Ultralow Power Spintronics

Advanced Functional Materials, EarlyView.
2D magnets and topological quantum materials enable ultralow‐power spintronics by combining robust magnetic order with symmetry‐protected, Berry‐curvature‐driven transport. Fundamentals of 2D anisotropy and spin‐orbit‐coupling induced band inversion are linked to scalable growth and vdW stacking.
Brahmdutta Dixit, Yifei Yang, Shawn Li, Yu‐Chia Chen, Qi Jia, Jian‐Ping Wang   +5 more
wiley   +1 more source

Structure-based membrane dome mechanism for Piezo mechanosensitivity

eLife, 2017
Mechanosensitive ion channels convert external mechanical stimuli into electrochemical signals for critical processes including touch sensation, balance, and cardiovascular regulation. The best understood mechanosensitive channel, MscL, opens a wide pore,
Yusong R Guo, Roderick MacKinnon
doaj   +1 more source

Thermodynamics of voltage-gated ion channels [PDF]

Biophysics Reports, 2018
Ion channels are essential for cellular signaling. Voltage-gated ion channels (VGICs) are the largest and most extensively studied superfamily of ion channels. They possess modular structural features such as voltage-sensing domains that encircle and form mechanical connections with the pore-forming domains.
Zhang, Xuejun C., Yang, Hanting, Liu, Zhenfeng, Sun, Fei   +3 more
openaire   +2 more sources

Actuating and Sensing Composites of Liquid Crystal Elastomers and Poly(ionic liquid)s

Advanced Functional Materials, EarlyView.
Ionic conductive, mechanically tough, flexible, and stretchable filaments of a composite material comprising a liquid crystal elastomer and a poly(ionic liquid) are produced through 3D printing, which exhibit large actuation strain under stimulation and electrical resistance variation in response to deformation or environmental condition changes. Their
Zeping Liu, Xiaofeng Zheng, Shaoxia Zhang, Long Xu, Meng Liu, Jeremy Baribeault St‐Germain, Yue Zhao   +6 more
wiley   +1 more source

Lipid-mediated hydrophobic gating in the BK potassium channel

Nature Communications
Structures of the large-conductance, calcium-activated potassium (BK) channel in the Ca2+ −bound and Ca2+ −free states have suggested that K+ conduction is not gated via a steric closure of the pore-lining helices of the channel, in contrast to the ...
Lucia Coronel, Giovanni Di Muccio, Brad S. Rothberg, Alberto Giacomello, Vincenzo Carnevale   +4 more
doaj   +1 more source

Voltage dependence of Hodgkin-Huxley rate functions for a multi-stage K channel voltage sensor within a membrane [PDF]

, 2014
The activation of a $K^+$ channel sensor in two sequential stages during a voltage clamp may be described as the translocation of a Brownian particle in an energy landscape with two large barriers between states.
Vaccaro, Samuel R.
core   +2 more sources