Results 121 to 130 of about 2,488,331 (299)

Voltage Gated Ion Entry Into Two‐dimensional Angstrom‐Scale Channels

open access: yesAdvanced Functional Materials, EarlyView.
We demonstrate voltage‐gated ion transport through artificial Å‐scale slit channels (∼4 Å high) formed by van der Waals assembly of 2D materials. At low electric fields, ions are excluded while water permeates. Above a threshold voltage, nonlinear hysteretic conduction emerges, driven by ion dehydration and concentration‐dependent barriers, mimicking ...
Solleti Goutham   +10 more
wiley   +1 more source

A range of voltage-clamp protocol designs for rapid capture of hERG kinetics [version 2; peer review: 3 approved]

open access: yesWellcome Open Research
We provide details of a series of short voltage-clamp protocols designed for gathering a large amount of information on hERG (Kv11.1) ion channel gating.
Chon Lok Lei   +5 more
doaj   +1 more source

Biodegradable Conductors for Implantable and Wearable Transient Bioelectronics

open access: yesAdvanced Functional Materials, EarlyView.
Biodegradable conductors are essential building blocks for transient bioelectronics, enabling temporary sensing, stimulation, and energy transfer while eliminating the need for device retrieval. This review summarizes biodegradable metals, conducting polymers, ionic conductors, and conductive composites, highlighting degradation mechanisms, material ...
Yicheng Zhu, Yijun Liu, Naoji Matsuhisa
wiley   +1 more source

Cooperative gating between ion channels

open access: yesGeneral physiology and biophysics, 2014
Cooperative gating between ion channels, i.e. the gating of one channel directly coupled to the gating of neighboring channels, has been observed in diverse channel types at the single-channel level. Positively coupled gating could enhance channel-mediated signaling while negative coupling may effectively reduce channel gating noise.
openaire   +3 more sources

Thermally Robust Room‐Temperature Interlayer Excitons in a Hybrid van der Waals Heterostructure

open access: yesAdvanced Functional Materials, EarlyView.
We report an optically active interlayer exciton in a hybrid van der Waals (PEA)2PbBr4/MoS2 heterostructure that remains thermally stable up to 400 K. The emission exhibits polarization anisotropy consistent with an out‐of‐plane optical transition‐dipole component and shows lifetime extension indicative of electron–hole separation.
Seoyeon Ko   +9 more
wiley   +1 more source

Parameter values for steady-state channel gating curves and time-constant curves for the different ion channels present in the model neuron.

open access: yes, 2018
Parameter values for steady-state channel gating curves and time-constant curves for the different ion channels present in the model neuron.
Alessio Franci (143351)   +3 more
core   +1 more source

Artemisinin‐Loaded Core‐Shell Microspheres Modulate Histone Lactylation to Remodel the Microenvironment for Cartilage Protection in Rheumatoid Arthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
ART@PLGA@GH‐A microspheres are developed via microfluidic technology for intra‐articular delivery of artemisinin. The system remodels rheumatoid arthritis microenvironments by regulating metabolic and inflammatory disorders, reducing lactate‐driven histone lactylation and cellular senescence, while restoring cartilage homeostasis and protecting joint ...
Shijie Meng   +10 more
wiley   +1 more source

The structure of a voltage gated potassium channel

open access: yes, 2010
Voltage gated potassium channels (Kv channels) are tetrameric ion channels, responsible for regulating the potassium component of the membrane potential in a large range of cell types ranging from mammalian excitable cells to bacteria. Attempts have been
Rogers, Nik
core   +1 more source

Reptation theory of ion channel gating

open access: yesBiophysical Journal, 1990
Reptation theory is a highly successful approach for describing polymer dynamics in entangled systems. In turn, this molecular process is the basis of viscoelasticity. We apply a modified version of reptation dynamics to develop an actual physical model of ion channel gating.
openaire   +2 more sources

Effects of hydrophobic mismatch and spontaneous curvature on ion channel gating with a hinge

open access: yes, 2018
We analyze the energetics of an ion-channel gating, focusing on effects of hydrophobic mismatch between the channel protein and the nearby lipid molecules, spontaneous curvature of monolayers, and thickness change of membranes.
이공주복
core   +1 more source

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