Results 181 to 190 of about 60,430 (260)

Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation

BMEMat, EarlyView.
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu, Nan Xu, Xin Li, Xiaowo Kang, Tieyuan Bian, Junsheng Lin, Hao Tang, Yinyin Bao, Lu Zhang, Hongyan Yuan, Mingxi Yao, Xingyu Jiang, Zhi Luo   +12 more
wiley   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

BMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng, Xiaomin Luo, Peng Zhang, Chen Yang, Yuniel Ma, Xinhua Liu   +5 more
wiley   +1 more source

Design of experiments‐guided membrane capture facilitates integration of continuous virus inactivation using Phi6 as a surrogate virus in an intensified downstream process

Biotechnology Progress, EarlyView.
Abstract The growing demand for cost‐efficient and flexible biomanufacturing has increased interest in process‐intensified downstream platforms. This study evaluates an intensified monoclonal antibody (mAb) purification sequence, where two unit operations traditionally performed in batch mode—Protein A capture and low pH virus inactivation (VI)—are ...
Mario Grünberg, Lisa Lipski, Gabriel Fisicaro, Thomas Duvignau, Karolina Meyer‐Heinrichs, Diana Carmen Mocsy, Thomas‐Josef Filz, Bastian Quaas, Alexandra Stützer   +8 more
wiley   +1 more source

Unveiling the Roles of Ti Species and Solvent in Propylene Epoxidation With H2O2 Over Titanosilicate‐1 Catalyst Through Density Functional Theory Insights

Carbon and Hydrogen, EarlyView.
This work employs density functional theory (DFT) calculations to identify the reaction mechanism and unveil the roles of Ti species and solvent in propylene epoxidation with H2O2 over TS‐1 catalyst. ABSTRACT The mechanism of propylene epoxidation catalyzed by distinct titanium (Ti) species within the TS‐1 framework was systematically explored through ...
Junxi Chen, Xue Wei, Xinyue Wang, Xiaowa Nie, Xinwen Guo   +4 more
wiley   +1 more source

Selective Oxidation Strategies for Cost‐Efficient Green Hydrogen Production via Hybrid Water Electrolysis

Carbon Energy, EarlyView.
Hybrid water electrolysis has emerged as a promising alternative to conventional electrolysis for sustainable hydrogen production. The economic potential of replacing water oxidation with organic substrates is assessed. For each substrate, representative electrocatalysts and mechanistic insights are reviewed to identify design principles for optimized ...
Conor Brennan‐Pollak, Lua Henderson, Cian Clarke, Maida A. Costa de Oliveira, Dídac A. Fenoll, Sreedhanya Pallilavalappil, Aswathy Babu, Shaista Jabeen, Pranav K. Gangadharan, Huabin Zhang, Suresh C. Pillai, Paula E. Colavita, Max García‐Melchor   +12 more
wiley   +1 more source

Ruthenium‐Titania Interface‐Mediated Water Activation for High Turnover Frequency in Alkaline Hydrogen Evolution

Carbon Energy, EarlyView.
Heterostructured interfaces can accelerate hydrogen evolution by improving water dissociation, yet their underlying mechanisms remain unclear. This study combines in situ Raman spectroscopy and density functional theory to reveal how the RuO2/TiO2 interface promotes both water dissociation and hydrogen adsorption, providing new insights into the ...
Dwi Sakti Aldianto Pratama, Andi Haryanto, Hyun Woo Lim, Chan Woo Lee   +3 more
wiley   +1 more source

Key Challenges for Commercializing Perovskite–Silicon Tandem Solar Cells

Carbon Energy, EarlyView.
This review discusses the scientific and technological challenges in advancing perovskite–silicon tandem solar cells (PSTSCs) from lab‐scale to commercial viability, focusing on long‐term stability, scalability, and economic feasibility. Key issues include intrinsic and extrinsic degradation factors, installation conditions, environmental impacts, and ...
Bilal Mehmood, Yuanyuan Qin, Abdul Sattar, Rabeea Eman, Faheem Abbas, Shan Wu, Yipeng Xu, Xu Zheng, Jiangying Lu, Wei Jiang, Jiankai Liu, Shudi Lu, Shizhong Yue, Zhijie Wang, Kong Liu, Xiaopeng Zheng, Shengchun Qu   +16 more
wiley   +1 more source

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

Chemistry – A European Journal, EarlyView.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

Construction of a CO2‐Fixing Compartment Using a Shape‐Transforming DNA Scaffold

Chemistry – A European Journal, EarlyView.
A shape‐transforming DNA scaffold encapsulates RuBisCO within a controllable, self‐contacting compartment that mimics the carboxysome. The scaffold switches between open and closed states, enabling direct comparison of identical enzyme populations in different microenvironments.
Hui Yang, Peng Lin, Surachada Chuaychob, Huyen Dinh, Mei Nakabayashi, Eiji Nakata, Takashi Morii   +6 more
wiley   +1 more source

It's a Gas: Bioconjugation With Vapor‐Phase Reagents

Chemistry – A European Journal, EarlyView.
Gaseous reagents are an emerging class of bioconjugation reagents that can offer alternative selectivity paradigms for the construction of precise bioconjugates. A variety of both inert and highly reactive gases have recently been developed for bioconjugation use.
Yuxuan Ding, Jun Ohata, Zachary T. Ball
wiley   +1 more source