Results 201 to 210 of about 2,991,834 (285)

High‐throughput development and scale‐up of recombinant adeno‐associated virus 5 anion‐exchange chromatography for high‐purity capsid separation

Biotechnology Progress, EarlyView.
High‐throughput anion‐exchange chromatography process development enables scalable purification of high‐purity recombinant adeno‐associated virus capsids. Abstract Recombinant adeno‐associated virus (rAAV) production commonly yields a high proportion of empty and partially filled capsids, necessitating downstream purification to enrich full capsids ...
Kevin Vera, Ivan Gajic, Praveen Kusumanchi, Angela Andaluz, Gabrielle Dela Pena, Clifford A. Froelich, Elizabeth Higgins, Jennifer Johnston, Seyed Pouria Motevalian   +8 more
wiley   +1 more source

DNA concentration in harvest affects retrovirus clearance capabilities of protein A chromatography

Biotechnology Progress, EarlyView.
Abstract Protein A chromatography is a key unit operation in biopharmaceutical purification, widely used to capture monoclonal antibodies (mAbs) from harvest cell culture fluid (HCCF). In addition to its primary function, protein A chromatography is also frequently tested for its ability to remove viruses. Although protein A specifically binds mAbs and
Lukas Döring, Sven Schubert, Nora Roos, Johannes Winderl, Annika Müller, Anna Ratermann, Matthias W. Kron, Jürgen Hubbuch   +7 more
wiley   +1 more source

Compositionally Tunable Interpolymer System for Charge-Selective Recovery of Gold Cyanide from Ferrocyanide-Rich Solutions. [PDF]

Polymers (Basel)
Suleimenova M, Jumadilov T, Gražulevičius J, Khimersen K, Mukanova M.   +4 more
europepmc   +1 more source

Development and application of a mechanistic model for protein A resolution of a bispecific antibody for process characterization and optimization

Biotechnology Progress, EarlyView.
Abstract Regeneron's bispecific technology, based on a fully human IgG antibody construct, consists of two distinct heavy chains and a common light chain co‐expressed in a single cell. The co‐expression of the two distinct heavy chains, one of which contains a dipeptide substitution that ablates Protein A binding, leads to the formation of three ...
Samantha Wadsworth, James Reilly, John Mattila, Christopher Cowan, Hanne Bak   +4 more
wiley   +1 more source

Synthesis and Evaluation of a Novel Cassava-Based Starbon-Type Mesoporous Catalyst. [PDF]

ACS Omega
Zabala MA, Bose S, Panqueba LJ, Orjuela A, Clark JH.   +4 more
europepmc   +1 more source

Graphene Materials for Sustainable Energy Applications: A Contemporary Perspective

Carbon Energy, EarlyView.
ABSTRACT Graphene has garnered significant attention as a promising material with great potential for contributing to sustainable energy initiatives, such as RE100 (100% renewable energy initiative) and CF100 (100% carbon‐free initiative). This review aims to explore the potential of graphene for advancing renewable energy applications by highlighting
Niraj Kumar, Seul‐Yi Lee, Roop L. Mahajan, Soo‐Jin Park   +3 more
wiley   +1 more source

Active Learning-Guided Optimization of Moisture Swing Adsorption for Direct Air Capture. [PDF]

Environ Sci Technol
Yu P, Zhang K, Shi X, Zheng Z, Zhang H.
europepmc   +1 more source

Boosting Sodium Storage Activity and Kinetics of Hard Carbon by Remodeling Oxygen Chemistry

Carbon Energy, EarlyView.
A surface oxygen remodeling strategy is proposed to finely furnish the pseudographitic structure of hard carbon with rich closed pores and expanded interlayer spacings. Accordingly, the sodiation reactivity and kinetics are greatly reinforced to afford an elevated capacity of 360 mAh g−1 and outstanding rate capability of 225 mAh g−1 at 2 A g−1 ...
Xingling Hu, Weijia He, Jian‐Gan Wang, Hao Xu, Xin Li, Delin Xia, Junhui Dong, Jianfang Wang, Na Huang, Yang Zhang, Yanlin Li, Ding Nan, Chunguang Wei   +12 more
wiley   +1 more source

Ion exchange resin-catalyzed epoxidation of sesame oil: effects of temperature and reaction time. [PDF]

Sci Rep
Ospino L, Rodriguez R, Loaiza A, Gonzalez JM, Ojeda-Delgado K, Sanchez-Tuirán E.   +5 more
europepmc   +1 more source

Recent Progress of Biomass‐Derived Nitrogen‐Doped Carbon Materials as Electrocatalysts: Carbonization, Functionalization, and Applications

Carbon Energy, EarlyView.
Integrating renewable energy with electrochemical conversion and storage is crucial for sustainable energy solutions. Nitrogen‐doped biomass‐derived carbon materials have emerged as effective catalysts for key reactions such as ORR, HER, and CO2RR. This review explores their synthesis, functionalization, characterization, and catalytic applications ...
Shilong Fu, Haiping Yang, Wiebren de Jong, Ruud Kortlever   +3 more
wiley   +1 more source