Results 31 to 40 of about 38,937 (242)

Ion mobility–mass spectrometry for structural proteomics [PDF]

Expert Review of Proteomics, 2012
Ion mobility coupled to mass spectrometry has been an important tool in the fields of chemical physics and analytical chemistry for decades, but its potential for interrogating the structure of proteins and multiprotein complexes has only recently begun to be realized. Today, ion mobility-mass spectrometry is often applied to the structural elucidation
Yueyang, Zhong, Suk-Joon, Hyung, Brandon T, Ruotolo   +2 more
openaire   +2 more sources

Electrospray Quadrupole Travelling Wave Ion Mobility Time-of-Flight Mass Spectrometry for the Detection of Plasma Metabolome Changes Caused by Xanthohumol in Obese Zucker (fa/fa) Rats

Metabolites, 2013
This study reports on the use of traveling wave ion mobility quadrupole time-of-flight (ToF) mass spectrometry for plasma metabolomics. Plasma metabolite profiles of obese Zucker fa/fa rats were obtained after the administration of different oral doses ...
Claudia S. Maier, Adrian F. Gombart, Jan F. Stevens, Yuan Jiang, Jeff Morré, Jay Kirkwood, Samanthi I. Wickramasekara, LeeCole Legette, Fereshteh Zandkarimi   +8 more
doaj   +1 more source

Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides

Nature Communications, 2020
Heparan sulfates (HS) contain functionally relevant structural motifs, but determining their monosaccharide sequence remains challenging. Here, the authors develop an ion mobility mass spectrometry-based method that allows unambiguous characterization of
Rebecca L. Miller, Scott E. Guimond, Ralf Schwörer, Olga V. Zubkova, Peter C. Tyler, Yongmei Xu, Jian Liu, Pradeep Chopra, Geert-Jan Boons, Márkó Grabarics, Christian Manz, Johanna Hofmann, Niclas G. Karlsson, Jeremy E. Turnbull, Weston B. Struwe, Kevin Pagel   +15 more
doaj   +1 more source

Ion mobility mass spectrometry for the study of mycobacterial mycolic acids

Scientific Reports, 2023
Lipids are highly structurally diverse molecules involved in a wide variety of biological processes. The involvement of lipids is even more pronounced in mycobacteria, including the human pathogen Mycobacterium tuberculosis, which produces a highly ...
Yi Liu, Nadhira Kaffah, Sufyan Pandor, Mark J. Sartain, Gerald Larrouy-Maumus   +4 more
doaj   +1 more source

Right in two: capabilities of ion mobility spectrometry for untargeted metabolomics

Frontiers in Molecular Biosciences, 2023
This mini review focuses on the opportunities provided by current and emerging separation techniques for mass spectrometry metabolomics. The purpose of separation technologies in metabolomics is primarily to reduce complexity of the heterogeneous systems
Tessa Moses, Karl Burgess
doaj   +1 more source

Sizing up DNA nanostructure assembly with native mass spectrometry and ion mobility

Nature Communications, 2022
Interest in oligonucleotide nanostructures has recently surged in basic and applied research. Here, the authors use native mass spectrometry and ion mobility to elucidate a prototypical hexameric DNA barrel structure as well as intermediates and ...
Jeroen F. van Dyck, Jonathan R. Burns, Kyle I. P. Le Huray, Albert Konijnenberg, Stefan Howorka, Frank Sobott   +5 more
doaj   +1 more source

Lipidomics by HILIC-Ion Mobility-Mass Spectrometry [PDF]

, 2019
Lipidomics is a rapidly growing field that enables the characterization of the entire lipidome in cells, tissues, or an organism. Changes in lipid metabolism and homeostasis caused by different disease states or drug treatments can be probed by lipidomics experiments, which can aid our understanding of normal physiology and disease pathology at the ...
Amy, Li, Kelly M, Hines, Libin, Xu
openaire   +2 more sources

Recommendations for Reporting Ion Mobility Mass Spectrometry Measurements [PDF]

Mass Spectrometry Reviews, 2018
Here we present a guide on ion mobility mass spectrometry experiments, which covers both linear and nonlinear methods: what is measured, how the measurements are done, and how to report the results, including the uncertainties on mobility and collision cross section values.
Gabelica, Valérie, Shvartsburg, Alexandre A, Afonso, Carlos, Barran, Perdita, Benesch, Justin L P, Bleiholder, Christian, Bowers, Michael T, Bilbao, Aivett, Bush, Matthew F, Campbell, J Larry, Campuzano, Iain D G, Causon, Tim, Clowers, Brian H, Creaser, Colin S, De Pauw, Edwin, Far, Johann, Fernandez-Lima, Francisco, Fjeldsted, John C, Giles, Kevin, Groessl, Michael, Hogan, Christopher J (Jr), Hann, Stephan, Kim, Hugh I, Kurulugama, Ruwan T, May, Jody C, McLean, John A, Pagel, Kevin, Richardson, Keith, Ridgeway, Mark E, Rosu, Frédéric Johanna R, Sobott, Frank, Thalassinos, Konstantinos, Valentine, Stephen J, Wyttenbach, Thomas   +33 more
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Mobilising ion mobility mass spectrometry for metabolomics

The Analyst, 2018
The benefits of adding data from ion mobility measurements to a mass spectrometry based metabolomics workflow are assessed using a panel of small molecules. Data is presented as collision cross section values and distributions.
Eleanor Sinclair, Katherine A. Hollywood, Cunyu Yan, Richard Blankley, Rainer Breitling, Perdita Barran   +5 more
openaire   +3 more sources

Application of Ion Mobility Mass Spectrometry in Food Analysis

Shipin gongye ke-ji
Ion mobility spectroscopy is a technique to characterize compounds based on the differences in the migration of sample ions under the combined action of electric field and air flow.
Bo SI, Yating GU, Chen YANG, Yongling LU, Lishuang LÜ   +4 more
doaj   +1 more source