Results 81 to 90 of about 2,056,696 (309)

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Ion-Mobility-Based Quantification of Surface-Coating-Dependent Binding of Serum Albumin to Superparamagnetic Iron Oxide Nanoparticles

, 2016
Protein binding and protein-induced nanoparticle aggregation are known to occur for a variety of nanomaterials, with the extent of binding and aggregation highly dependent on nanoparticle surface properties.
Seongho Jeon (1418680), Gary Van Schooneveld (2878295), John C. Bischof (1963219), Christopher J. Hogan (684955), Derek R. Oberreit (540645), Zhe Gao (1537531), Christy L. Haynes (525267)   +6 more
core   +1 more source

Collision cross sections of negative cluster ions of phosphoric acid in N2 determined by drift tube ion mobility and their use in travelling wave ion mobility [PDF]

, 2019
International audienceTravelling wave ion mobility usually uses a calibration procedure to determine collision cross sections. Here, we investigate phosphoric acid cluster anions as possible calibrants to increase the pool of reference ions for singly ...
Afonso, Carlos, Groessl, Michael, Lavanant, Hélène   +2 more
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

From Analysis to Assessment: Machine Learning for Non-Target Screening of Pollutants Using Chromatography Coupled with (Ion Mobility) Mass Spectrometry

Toxics
The growing diversity of anthropogenic chemicals in the environment far exceeds the scope of routine analytical monitoring. Non-target screening (NTS) using high-resolution mass spectrometry (HRMS) has thus emerged to discover unknown organic ...
Dongshan Lin, Zhenyue Wang, Jiaqi Liao, Nan Li, Xiaolei Li   +4 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Experimental Evidence on the Effect of Temperature on the Performance of a Lithium-Ion Battery

Batteries
The current energy transition highlights the importance not only of energy production, but also of its efficient storage, for which lithium-ion batteries are currently the leading technology.
Maurizio Bressan, Elena Campagnoli, Valter Giaretto   +2 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Space Charge Transport Characteristic Considering the Non-Uniform Electric Effect of Ion Mobility

IEEE Access, 2020
Oil-paper insulation is the main insulating medium of converter transformers. Space charge can result in the distortion of electric field in oil-paper insulation, hence it's necessary to analyze the space charge transport characteristic and its influence
Zhaoxiang Zhang, Kai Yang, Cheng Chi, Fan Yang, Li Liu, Shaohua Wang   +5 more
doaj   +1 more source