Results 61 to 70 of about 157,015 (313)

Ion-Mobility-Derived Collision Cross Section as an Additional Identification Point for Multiresidue Screening of Pesticides in Fish Feed

, 2016
Ion mobility spectrometry allows for the measurement of the collision cross section (CCS), which provides information about the shape of an ionic molecule in the gas phase. Although the hyphenation of traveling-wave ion mobility spectrometry (TWIMS) with
Jorge Regueiro (2808613), Noelia Negreira (786310), Marc H.G. Berntssen (3330273)   +2 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Ion-Mobility Mass Spectrometry of Glycans and Glycopeptides Using Both Intact and Glycan Sequencing Approaches In Positive Ion Mode Facilitates Glycan Isomer and Glycan Motif Identification

, 2020
High resolution glycan analysis has become an important part of biopharmaceutical API production and quality control. Liquid chromatography (LC) is now a well-established technique in this field but the resolution of similar isomeric glycan structures is
Sabine, Flitsch, jien nee, tai, Edward, Pallister, Yuansheng, Yang, Say-Kong, Ng, Pauline, Rudd, Shi-Jie, Tay, ian, walsh, Matthew, Choo, Terry, Nguyen-Khuong   +9 more
core   +2 more sources

A Study on the Reliability Test of a Lithium Battery in Medical Electric Wheelchairs for Vulnerable Drivers

Applied Sciences, 2019
There are test items for lithium-ion batteries in reliability testing for automobiles and motorcycles, but equivalent test items have not yet been established for mobility scooters (also known as electronic wheelchairs).
Sunwoo Yuk, Kiwon Choi, Sang-Geon Park, Sukmin Lee   +3 more
doaj   +1 more source

Ion Mobility-Derived Collision Cross-Sections Add Extra Capability in Distinguishing Isomers and Compounds with Similar Retention Times: The Case of Aphidicolanes

Marine Drugs, 2022
The hyphenation of ion mobility spectrometry with high-resolution mass spectrometry has been widely used in the characterization of various metabolites. Nevertheless, such a powerful tool remains largely unexplored in natural products research, possibly ...
Jinmei Xia, Wenhai Xiao, Xihuang Lin, Yiduo Zhou, Peng Qiu, Hongkun Si, Xiaorong Wu, Siwen Niu, Zhuhua Luo, Xianwen Yang   +9 more
doaj   +1 more source

OC-163 identification of inflammatory bowel disease (IBD) using field asymmetric ion mobility spectrometry (FAIMS) [PDF]

, 2012
Introduction Resident colonic bacteria, principally anaerobes and firmicutes, ferment undigested fibre. The resultant volatile organic compounds (VOCs) formed are dissolved in the faeces but also absorbed and excreted in the urine.
Thomas, M. G., Hetherington, E., Arasaradnam, Ramesh P., Ouaret, N., Covington, James A., Quraishi, M. N., Nwokolo, Chuka U., Bardhan, Karna Dev   +7 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Protein shape sampled by ion mobility mass spectrometry consistently improves protein structure prediction

Nature Communications, 2022
Collision cross sections (CCS) from ion mobility mass spectrometry provide information about protein shape and size. Here, the authors develop an algorithm to predict CCS and integrate experimental ion mobility data into Rosetta-based molecular modelling
SM Bargeen Alam Turzo, Justin T. Seffernick, Amber D. Rolland, Micah T. Donor, Sten Heinze, James S. Prell, Vicki H. Wysocki, Steffen Lindert   +7 more
doaj   +1 more source

Separation Abilities of Capillary Electrophoresis Coupled with Ion Mobility Mass Spectrometry for the Discrete Detection of Sequence Isomeric Peptides

Separations, 2022
The separation and discrete detection of isomeric sequence peptides with similar properties are important tasks for analytical science. Three different peptide isomers of 12 amino-acid residues long, containing direct and reverse regions of the alanine ...
Yury E. Glazyrin, Gleb G. Mironov, Anna S. Kichkailo, Maxim V. Berezovski   +3 more
doaj   +1 more source

Ion Mobility-Mass Correlation Trend Line Separation of Glycoprotein Digests without Deglycosylation

, 2013
A high-throughput ion mobility mass spectrometer (IMMS) was used to rapidly separate and analyze peptides and glycopeptides derived from glycoproteins.
Bendiak, Brad, Siems, William F, Li, Hongli, Hill, Herbert H, Gang, David R   +4 more
core   +1 more source