Results 11 to 20 of about 5,630 (192)

Negative Reactant Ion Formation in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]

Journal of the American Society for Mass Spectrometry, 2020
Due to the operation at background pressures between 10-40 mbar and high reduced electric field strengths of up to 120 Td, the ion–molecule reactions in High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) differ from those in classical ambient pressure IMS.
Maria Allers, Ansgar T. Kirk, Bennet Timke, Duygu Erdogdu, Walter Wissdorf, Thorsten Benter, Stefan Zimmermann   +6 more
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Positive Reactant Ion Formation in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]

Journal of the American Society for Mass Spectrometry, 2020
In contrast to classical Ion Mobility Spectrometers (IMS) operating at ambient pressure, the High Kinetic Energy Ion Mobility Spectrometer (HiKE-IMS) is operated at reduced pressures of between 10 and 40 mbar and higher reduced electric field strengths of up to 120 Td.
Maria Allers, Ansgar T. Kirk, Manuel Eckermann, Christoph Schaefer, Duygu Erdogdu, Walter Wissdorf, Thorsten Benter, Stefan Zimmermann   +7 more
openaire   +2 more sources

Targeted glucocorticoid analysis using ion mobility-mass spectrometry (IM-MS)

Journal of Mass Spectrometry and Advances in the Clinical Lab, 2022
Ion mobility-mass spectrometry (IM-MS) is an emerging technique in the -omics fields that has broad potential applicability to the clinical lab. As a rapid, gas-phase structure-based separation technique, IM-MS offers promise in isomer separations and can be easily combined with existing LC-MS methods (i.e., LC-IM-MS).
Shon P. Neal, Katie M. Wilson, Diana C. Velosa, Christopher D. Chouinard   +3 more
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Laserspray ionization (LSI) ion mobility spectrometry (IMS) mass spectrometry [PDF]

Journal of the American Society for Mass Spectrometry, 2010
A simple device is described for desolvation of highly charged matrix/analyte clusters produced by laser ablation leading to multiply charged ions that are analyzed by ion mobility spectrometry-mass spectrometry. Thus, for example, highly charged ions of ubiquitin and lysozyme are cleanly separated in the gas phase according to size and mass (shape and
Inutan, Ellen, Trimpin, Sarah
openaire   +2 more sources

High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) at 40 mbar [PDF]

Journal of the American Society for Mass Spectrometry, 2020
High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) are usually operated at an absolute pressure of 20 mbar reaching high reduced electric field strengths of up to 125 Td for controlled reaction kinetics. This significantly increases the linear range and limits chemical cross sensitivities.
Florian Schlottmann, Ansgar T. Kirk, Maria Allers, Alexander Bohnhorst, Stefan Zimmermann   +4 more
openaire   +2 more sources

Ion mobility spectrometry‐mass spectrometry (IMS‐MS) of small molecules: Separating and assigning structures to ions [PDF]

Mass Spectrometry Reviews, 2012
AbstractThe phenomenon of ion mobility (IM), the movement/transport of charged particles under the influence of an electric field, was first observed in the early 20th Century and harnessed later in ion mobility spectrometry (IMS). There have been rapid advances in instrumental design, experimental methods, and theory together with contributions from ...
Lapthorn, Cris, Pullen, Frank, Chowdhry, Babur Z.   +2 more
openaire   +3 more sources

Separation of different ion structures in atmospheric pressure photoionization-ion mobility spectrometry-mass spectrometry (APPI-IMS-MS) [PDF]

Journal of the American Society for Mass Spectrometry, 2010
This study demonstrates how positive ion atmospheric pressure photoionization-ion mobility spectrometry-mass spectrometry (APPI-IMS-MS) can be used to produce different ionic forms of an analyte and how these can be separated. When hexane:toluene (9:1) is used as a solvent, 2,6-di-tert-butylpyridine (2,6-DtBPyr) and 2,6-di-tert-4-methylpyridine (2,6 ...
Laakia, Jaakko, Adamov, Alexey, Jussila, Matti, Pedersen, Christian S., Sysoev, Alexey A., Kotiaho, Tapio   +5 more
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Enhancing Lipidomics With High-Resolution Ion Mobility-Mass Spectrometry. [PDF]

Proteomics
ABSTRACT Lipids, indispensable yet structurally intricate biomolecules, serve as critical regulators of cellular function and disease progression. Conventional lipidomics, constrained by limited resolution for isomeric and low‐abundance species, has been transformed by ion mobility‐mass spectrometry (IM‐MS).
Lu G, Xu S, Huang P, Li L.
europepmc   +2 more sources

Flexible Drift Tube for High Resolution Ion Mobility Spectrometry (Flex-DT-IMS) [PDF]

Analytical Chemistry, 2020
This paper describes, in detail, the development of a novel, low-cost, and flexible drift tube (DT) along with an associated ion mobility spectrometer system. The DT is constructed from a flexible printed circuit board (PCB), with a bespoke "dog-leg" track design, that can be rolled up for ease of assembly. This approach incorporates a shielding layer,
Barry L. Smith, Cedric Boisdon, Iain S. Young, Thanit Praneenararat, Tirayut Vilaivan, Simon Maher   +5 more
openaire   +2 more sources

Fast Sensing of Hydrogen Cyanide (HCN) Vapors Using a Hand-Held Ion Mobility Spectrometer with Nonradioactive Ionization Source

Sensors, 2021
Sensitive real-time detection of vapors produced by toxic industrial chemicals (TICs) always represents a stringent priority. Hydrogen cyanide (HCN) is definitely a TIC, being widely used in various industries and as an insecticide; it is a reactive ...
Victor Bocos-Bintintan, Ileana Andreea Ratiu   +1 more
doaj   +1 more source