Results 21 to 30 of about 20,265 (247)

High-Resolution Ion Mobility Spectrometry Mass Spectrometry for Isomeric Separation of Prostanoids after Girard's reagent T Derivatization [PDF]

open access: yes, 2023
RATIONALE: Isomeric separation of prostanoids is often a challenge and requires chromatography and time-consuming sample preparation. Multiple prostanoid isomers have distinct in vivo functions crucial to understand the inflammation process, including ...
Rob J. Vreeken   +26 more
core   +1 more source

Ion mobility spectrometry-tandem mass spectrometry strategies for the on-line monitoring of a continuous microflow reaction [PDF]

open access: yes, 2022
Continuous flow chemistry is an efficient, sustainable and green approach for chemical synthesis that surpasses some of the limitations of the traditional batch chemistry.
Han, P.L., Hadavi, D., Honing, M.
core   +1 more source

Ion Mobility–Mass Spectrometry for Bioanalysis

open access: yesSeparations, 2021
This paper aims to cover the main strategies based on ion mobility spectrometry (IMS) for the analysis of biological samples. The determination of endogenous and exogenous compounds in such samples is important for the understanding of the health status ...
Xavier Garcia   +4 more
doaj   +1 more source

Integrating the potential of ion mobility spectrometry-mass spectrometry in the separation and structural characterisation of lipid isomers

open access: yesFrontiers in Molecular Biosciences, 2023
It is increasingly evident that a more detailed molecular structure analysis of isomeric lipids is critical to better understand their roles in biological processes.
Sandra M. Camunas-Alberca   +6 more
doaj   +1 more source

Collision-Induced Unfolding of Native-like Protein Ions Within a Trapped Ion Mobility Spectrometry Device [PDF]

open access: yes, 2021
Native mass spectrometry and collision-induced unfolding (CIU) workflows continue to grow in utilization due to their abil-ity to rapidly characterize protein conformation and stability.
Katherine, Graham   +3 more
core   +1 more source

Uncovering the behaviour of ions in the gas-phase to predict the ion mobility separation of isomeric steroid compounds [PDF]

open access: yes, 2022
Bile acids are steroid compounds involved in biological mechanisms of neurodegenerative diseases making them potential biomarkers for diagnosis or treatment. These compounds exist as structural and conformational isomers, which hinder distinguishing them
Porta Siegel, Tiffany   +3 more
core   +1 more source

Discrimination of different edible vegetable oils based on GC-IMS and SIMCA

open access: yesCyTA - Journal of Food, 2023
Ion mobility spectrometry coupled to gas-chromatographic (GC-IMS) is tested regarding their ability to analyze various refined edible vegetable oils, including sunflower seed, rapeseed, sesame, soybean, peanut, corn, camellia, linseed, walnut, coconut ...
Dechun Geng   +3 more
doaj   +1 more source

Advances in Ion Mobility Spectrometry-Mass Spectrometry (IMS-MS)-Based Techniques for Elucidating Higher-Order Protein Structures [PDF]

open access: yes, 2020
Despite its great success in the field of proteomics, mass spectrometry has limited use for determining structural details of peptides, proteins, and their assemblies.
SEO, JONGCHEOL
core   +1 more source

Sensing Precursors of Illegal Drugs—Rapid Detection of Acetic Anhydride Vapors at Trace Levels Using Photoionization Detection and Ion Mobility Spectrometry

open access: yesMolecules, 2020
Sensitive real-time detection of vapors produced by the precursors, reagents and solvents used in the illegal drugs manufacture represents a priority nowadays.
Victor Bocos-Bintintan   +4 more
doaj   +1 more source

Collision Cross Section Prediction with Molecular Fingerprint Using Machine Learning

open access: yesMolecules, 2022
High-resolution mass spectrometry is a promising technique in non-target screening (NTS) to monitor contaminants of emerging concern in complex samples. Current chemical identification strategies in NTS experiments typically depend on spectral libraries,
Fan Yang   +3 more
doaj   +1 more source

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