Results 11 to 20 of about 7,880 (221)

Ion mobility spectrometry–mass spectrometry (IMS–MS) for on- and offline analysis of atmospheric gas and aerosol species [PDF]

Atmospheric Measurement Techniques, 2016
Measurement techniques that provide molecular-level information are needed to elucidate the multiphase processes that produce secondary organic aerosol (SOA) species in the atmosphere. Here we demonstrate the application of ion mobility spectrometry-mass
J. E. Krechmer, M. Groessl, X. Zhang, H. Junninen, P. Massoli, A. T. Lambe, J. R. Kimmel, M. J. Cubison, S. Graf, Y.-H. Lin, S. H. Budisulistiorini, H. Zhang, J. D. Surratt, R. Knochenmuss, J. T. Jayne, D. R. Worsnop, J.-L. Jimenez, M. R. Canagaratna   +17 more
doaj   +6 more sources

Laserspray Ionization (LSI) Ion Mobility Spectrometry (IMS) Mass Spectrometry [PDF]

Journal of the American Society for Mass Spectrometry, 2010
A simple device is described for desolvation of highly charged matrix/analyte clusters produced by laser ablation leading to multiply charged ions that are analyzed by ion mobility spectrometry-mass spectrometry. Thus, for example, highly charged ions of
Inutan, Ellen, Trimpin, Sarah
core   +3 more sources

Separation of Different Ion Structures in Atmospheric Pressure Photoionization-Ion Mobility Spectrometry-Mass Spectrometry (APPI-IMS-MS) [PDF]

Journal of the American Society for Mass Spectrometry, 2010
This study demonstrates how positive ion atmospheric pressure photoionization-ion mobility spectrometry-mass spectrometry (APPI-IMS-MS) can be used to produce different ionic forms of an analyte and how these can be separated.
Kotiaho, Tapio, Adamov, Alexey, Sysoev, Alexey A., Laakia, Jaakko, Jussila, Matti, Pedersen, Christian S.   +5 more
core   +3 more sources

Implementation of an Open-Source Multiplexing Ion Gate Control for High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS)

Journal of the American Society for Mass Spectrometry, 2023
With ion mobility spectrometry increasingly used in mass spectrometry to enhance separation by increasing orthogonality, low ion throughput is a challenge for the drift-tube ion mobility experiment. The High Kinetic Energy Ion Mobility Spectrometer (HiKE-
Cameron N. Naylor (16025359), Nic Solle (16025362), Brian H. Clowers, Florian Schlottmann (11026114), Florian Schlottmann, Stefan Zimmermann, Brian H. Clowers (830212), Stefan Zimmermann (1694173), Cameron N. Naylor, Nic Solle   +9 more
core   +5 more sources

The origin of isomerization of aniline revealed by high kinetic energy ion mobility spectrometry (HiKE-IMS)

Physical Chemistry Chemical Physics, 2022
Although aniline is a relatively simple small molecule, the origin of its two peaks observed in ion mobility spectrometry (IMS) has remained under debate for at least 30 years. First hypothesized as a difference in protonation site (amine vs.
Zimmermann, Stefan, Schaefer, Christoph, Naylor, Cameron N., Kirk, Ansgar T.   +3 more
core   +3 more sources

Resolving Isomeric Structures in Natural Complex Carbohydrates: A Comparative Study of SLIM and Cyclic Ion Mobility Platforms. [PDF]

Rapid Commun Mass Spectrom
ABSTRACT Rationale Recent advances in ion mobility mass spectrometry (IMS) have led to the development of high‐resolution platforms such as cyclic IMS and SLIM IMS (structures for lossless ion manipulations), both offering enhanced capabilities for resolving complex biomolecular conformations.
Benazza R, Harrilal CP, Ibrahim YM, Fanuel M, Ropartz D, Rogniaux H.   +5 more
europepmc   +2 more sources

A Combined MS/MS and IMS Study Into the Fragmentation Pathway of Nifedipine. [PDF]

J Mass Spectrom
ABSTRACT Collision‐induced dissociation (CID) of small molecules, typically with a molecular mass below 1500 Da, is widely applied for the structural identification of drug metabolites, synthetic by‐products and unknown compounds. Nonetheless, the interpretation of MS/MS spectra derived from protonated or sodiated molecules mainly relies on the ...
Han P, Thomassen N, Honing M.
europepmc   +2 more sources

Liquid Atmospheric Pressure MALDI (LAP-MALDI) Mass Spectrometry: A Versatile Tool for the Characterization of Synthetic Polymers. [PDF]

Rapid Commun Mass Spectrom
ABSTRACT Rationale Liquid atmospheric pressure matrix‐assisted laser desorption/ionization (LAP‐MALDI) mass spectrometry (MS) has previously been applied to the analysis of biopolymers such as peptides, proteins, and DNA, producing ESI‐like multiply charged analyte ions.
Kowalczyk AE, Brown J, Morris M, Cramer R.   +3 more
europepmc   +2 more sources

Sheath-Liquid CE-MS Interface: A Robust Infusion Platform for Native IMS-MS Analysis of Protein Assemblies and Their Conformers. [PDF]

J Mass Spectrom
ABSTRACT Dynamic protein complexes are central to cellular function, but capturing their native architectures remains challenging. While native ion mobility spectrometry–mass spectrometry (IMS‐MS) can characterize these assemblies, its broader adoption is limited by the need for robust and automated sample introduction platforms.
Pathak K, Brinkman D, Gomes FP.
europepmc   +2 more sources

Characterization of Grape Cane Stilbenoids and Their Photo-Degradation Products by HPLC-DAD Coupled With Trapped Ion Mobility Spectrometry and High-Resolution Tandem Mass Spectrometry. [PDF]

Rapid Commun Mass Spectrom
ABSTRACT Rationale Bioactive (E)‐stilbenoids in vine extracts are prone to light‐induced transformation into the respective (Z)‐isomers and further degradation products, often resulting in a loss of bioactivity. We sought to study stilbenoid degradation beyond that of the well‐researched resveratrol due to the high diversity of stilbenoids in nature ...
Besrukow P, Schnitker FA, Schweiggert R, Steingass CB.   +3 more
europepmc   +2 more sources