Results 11 to 20 of about 20,265 (247)

Laserspray ionization (LSI) ion mobility spectrometry (IMS) mass spectrometry [PDF]

Journal of the American Society for Mass Spectrometry, 2010
A simple device is described for desolvation of highly charged matrix/analyte clusters produced by laser ablation leading to multiply charged ions that are analyzed by ion mobility spectrometry-mass spectrometry. Thus, for example, highly charged ions of ubiquitin and lysozyme are cleanly separated in the gas phase according to size and mass (shape and
Inutan, Ellen, Trimpin, Sarah
core   +5 more sources

Ion mobility spectrometry‐mass spectrometry (IMS‐MS) of small molecules: Separating and assigning structures to ions [PDF]

Mass Spectrometry Reviews, 2012
AbstractThe phenomenon of ion mobility (IM), the movement/transport of charged particles under the influence of an electric field, was first observed in the early 20th Century and harnessed later in ion mobility spectrometry (IMS). There have been rapid advances in instrumental design, experimental methods, and theory together with contributions from ...
Lapthorn, Cris, Pullen, Frank, Chowdhry, Babur Z.   +2 more
core   +7 more sources

Rapid Characterization of Per- and Polyfluoroalkyl Substances (PFAS) by Ion Mobility Spectrometry–Mass Spectrometry (IMS-MS) [PDF]

Analytical Chemistry, 2020
Per- and polyfluoroalkyl substances (PFAS) are an ensemble of persistent organic pollutants of global interest because of their associations with adverse health outcomes. Currently, environmental PFAS pollution is prolific as a result of the widespread manufacturing of these compounds and their chemical persistence.
James N. Dodds, Zachary R. Hopkins, Detlef R. U. Knappe, Erin S. Baker   +3 more
openaire   +3 more sources

Separation of different ion structures in atmospheric pressure photoionization-ion mobility spectrometry-mass spectrometry (APPI-IMS-MS) [PDF]

Journal of the American Society for Mass Spectrometry, 2010
This study demonstrates how positive ion atmospheric pressure photoionization-ion mobility spectrometry-mass spectrometry (APPI-IMS-MS) can be used to produce different ionic forms of an analyte and how these can be separated. When hexane:toluene (9:1) is used as a solvent, 2,6-di-tert-butylpyridine (2,6-DtBPyr) and 2,6-di-tert-4-methylpyridine (2,6 ...
Laakia, Jaakko, Adamov, Alexey, Jussila, Matti, Pedersen, Christian S., Sysoev, Alexey A., Kotiaho, Tapio   +5 more
openaire   +4 more sources

High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) at 40 mbar [PDF]

Journal of the American Society for Mass Spectrometry, 2020
High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) are usually operated at an absolute pressure of 20 mbar reaching high reduced electric field strengths of up to 125 Td for controlled reaction kinetics. This significantly increases the linear range and limits chemical cross sensitivities.
Florian Schlottmann, Ansgar T. Kirk, Maria Allers, Alexander Bohnhorst, Stefan Zimmermann   +4 more
openaire   +3 more sources

Flexible Drift Tube for High Resolution Ion Mobility Spectrometry (Flex-DT-IMS) [PDF]

Analytical Chemistry, 2020
This paper describes, in detail, the development of a novel, low-cost, and flexible drift tube (DT) along with an associated ion mobility spectrometer system. The DT is constructed from a flexible printed circuit board (PCB), with a bespoke "dog-leg" track design, that can be rolled up for ease of assembly. This approach incorporates a shielding layer,
Barry L. Smith, Cedric Boisdon, Iain S. Young, Thanit Praneenararat, Tirayut Vilaivan, Simon Maher   +5 more
openaire   +3 more sources

The potential of ion mobility spectrometry (IMS) for detection of 2,4,6-trichloroanisole (2,4,6-TCA) in wine

Talanta, 2012
The off-flavor of "tainted wine" is attributed mainly to the presence of 2,4,6-trichloroanisole (2,4,6-TCA) in the wine. In the present study the atmospheric pressure gas-phase ion chemistry, pertaining to ion mobility spectrometry, of 2,4,6-trichloroanisole was investigated.
Karpas, Zeev, Guamán Novillo, Ana Verónica, Calvo, Daniel, Pardo Martínez, Antonio, Marco Colás, Santiago   +4 more
openaire   +4 more sources

Field-Dependent Reduced Ion Mobilities of Positive and Negative Ions in Air and Nitrogen in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]

Journal of the American Society for Mass Spectrometry, 2020
In High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS), ions are formed in a reaction region and separated in a drift region, which is similar to classical drift tube ion mobility spectrometers (IMS) operated at ambient pressure. However, in contrast to the latter, the HiKE-IMS is operated at a decreased background pressure of 10–40 mbar and ...
Maria Allers, Ansgar T. Kirk, Christoph Schaefer, Duygu Erdogdu, Walter Wissdorf, Thorsten Benter, Stefan Zimmermann   +6 more
openaire   +3 more sources

Implementation of an Open-Source Multiplexing Ion Gate Control for High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]

Journal of the American Society for Mass Spectrometry, 2023
With ion mobility spectrometry increasingly used in mass spectrometry to enhance separation by increasing orthogonality, low ion throughput is a challenge for the drift-tube ion mobility experiment. The High Kinetic Energy Ion Mobility Spectrometer (HiKE-IMS) is no exception and routinely uses duty cycles of less than 0.1%. Multiplexing techniques such
Cameron N. Naylor, Brian H. Clowers, Florian Schlottmann, Nic Solle, Stefan Zimmermann   +4 more
core   +8 more sources

The origin of isomerization of aniline revealed by high kinetic energy ion mobility spectrometry (HiKE-IMS) [PDF]

Physical Chemistry Chemical Physics, 2023
Three ion mobility peaks of 4-fluoroaniline, including the para-protonated and molecular ion species, when measured with a high-kinetic energy ion mobility spectrometer and peak abundances depend only on the ionization settings.
Cameron N. Naylor, Christoph Schaefer, Ansgar T. Kirk, Stefan Zimmermann   +3 more
openaire   +4 more sources