EM∩IM: software for relating ion mobility mass spectrometry and electron microscopy data [PDF]
The Analyst, 2016 EM∩IM enables the calculation of collision cross-sections from electron density maps obtained, for example, by means of transmission electron microscopy. This capability will further aid the integration of ion mobility mass spectrometry with modern structural biology.
Degiacomi, M, Benesch, J
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Implementation of a flexible, open-source platform for ion mobility spectrometry
HardwareX, 2018 When operated as a stand-alone device, an ion mobility spectrometer (IMS) routinely offers low limits of detection (pptv-range) for gas-phase analytes even for measurement times less than a second.
Tobias Reinecke, Brian H. Clowers
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Molecular Cages as Probes in Indicator Displacement Assays: The Case of Scopolamine Detection
Angewandte Chemie, EarlyView.In this research, we show the concept of molecular cages as probes in indicator displacement assays, focusing on scopolamine detection, a drug often used in drug‐facilitated sexual assaults. Drug sensing occurs via the drug‐induced transformation of non‐emissive [Fluorescein2⊂Cage] complex into [Scopolamine⊂Catenane] and highly emissive free ...
Giovanni Montà‐González +5 more
wiley +2 more sources
Assignment of polymorphic species of insulin analogues in ion mobility mass spectroscopy
Data in Brief, 2017 Electrospray ionization – ion mobility spectrometry – mass spectrometry (ESI–IMS–MS) allows the identification of protein polymorphic distribution of protein conformers and oligomers.
Maely P. Fávero-Retto +4 more
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Separations, 2023 In this study, star anise (Illicium verum) essential oils (SAEOs) were extracted by hydrodistillation (HD), ethanol solvent extraction (ESE), supercritical CO2 (SCD) and subcritical extraction (SE) via electronic nose (E-nose), gas chromatography-mass ...
Xianghua Chai +6 more
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Recombinant "IMS TAG" proteins : a new method for validating bottom-up matrix-assisted laser desorption/ionisation ion mobility separation mass spectrometry imaging [PDF]
, 2013 Rationale - Matrix assisted laser desorption ionisation mass spectrometry imaging (MALDI-MSI) provides a methodology to map the distribution of peptides generated by in situ tryptic digestion of biological tissue.
Beynon +22 more
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Evaporation and Discharge Dynamics of Highly Charged Multicomponent Droplets Generated by Electrospray Ionization [PDF]
, 2010 We investigate the Rayleigh discharge and evaporation dynamics of highly charged two-component droplets consisting principally of methanol with 2-methoxyethanol, tert-butanol, or m-nitrobenzyl alcohol.
Beauchamp, J. L., Grimm, Ronald L.
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Characterization of Amyloid Oligomers by Electrospray Ionization-Ion Mobility Spectrometry-Mass Spectrometry (ESI-IMS-MS) [PDF]
, 2016 Soluble oligomers formed during the self-assembly of amyloidogenic peptide and protein species are generally thought to be highly toxic. Consequently, thorough characterization of these species is of much interest in the quest for effective therapeutics and for an enhanced understanding of amyloid fibrillation pathways.
Scarff, CA, Ashcroft, AE, Radford, SE
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Metabolites, 2013 This study reports on the use of traveling wave ion mobility quadrupole time-of-flight (ToF) mass spectrometry for plasma metabolomics. Plasma metabolite profiles of obese Zucker fa/fa rats were obtained after the administration of different oral doses ...
Claudia S. Maier +8 more
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Software Tools and Approaches for Compound Identification of LC-MS/MS Data in Metabolomics. [PDF]
, 2018 The annotation of small molecules remains a major challenge in untargeted mass spectrometry-based metabolomics. We here critically discuss structured elucidation approaches and software that are designed to help during the annotation of unknown compounds.
Blaženović, Ivana +3 more
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