Results 81 to 90 of about 5,630 (192)

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

The FEBS Journal, Volume 293, Issue 6, Page 1681-1707, March 2026.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk, Kamil Steczkiewicz, Mariusz Radkiewicz, Paweł Link‐Lenczowski, Przemysław Surowiecki, Karolina Sztompka, Kariona A. Grabińska, Jacek K. Nowak, Liliana Surmacz   +8 more
wiley   +1 more source

Toward Timely Diagnosis of Pancreatic Cancer: Revolutionizing Early Detection Through Genomics, Artificial Intelligence, and Noninvasive Biomarkers

Journal of Gastroenterology and Hepatology, Volume 41, Issue 3, Page 895-913, March 2026.
ABSTRACT Background Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive cancers, typically diagnosed at an advanced stage due to its subtle and often absent early symptoms. Despite representing only 3% of new cancer cases, it is projected to become the second leading cause of cancer‐related deaths by 2030.
Muhammad Masroor Hussain, Sana Qammar, Ju‐Mei Wang, Ao‐Qiang Zhai, Fu‐yu Li, Hai‐jie Hu   +5 more
wiley   +1 more source

Artificial neural networks for the prediction of peptide drift time in ion mobility mass spectrometry

BMC Bioinformatics, 2010
Background There is an increasing usage of ion mobility-mass spectrometry (IMMS) in proteomics. IMMS combines the features of ion mobility spectrometry (IMS) and mass spectrometry (MS).
Plasencia Manolo, Valentine Steve, Wang Bing, Raghuraman Sriram, Zhang Xiang   +4 more
doaj   +1 more source

Dual-drift Tube Ion Mobility Spectrometry Based on Corona Discharge Ionization Source

Zhipu Xuebao
Ion mobility spectrometry (IMS) is a trace detection technique operating at atmospheric pressure. It is widely utilized in various fields, such as explosives and drug detection, chemical warfare agent detection, and biomedical applications, due to its ...
Xu ZHANG, Yu SONG, Yuan-jiang LUO, Wan-jun LI, Ling-wen KONG, Lei XIA, Ya-wei LIU, Cheng-yin SHEN, Chao-qun HUANG, Yan-nan CHU   +9 more
doaj   +1 more source

Multi-Capillary Column-Ion Mobility Spectrometry of Volatile Metabolites Emitted by Saccharomyces Cerevisiae

Metabolites, 2014
Volatile organic compounds (VOCs) produced during microbial fermentations determine the flavor of fermented food and are of interest for the production of fragrances or food additives.
Christoph Halbfeld, Birgitta E. Ebert, Lars M. Blank   +2 more
doaj   +1 more source

Fingerprinting of Green Arabica Coffee Volatile Organic Compounds (VOCs): HS-GC-IMS Versus GC × GC-MS

International Journal of Food Science
This study compared two nontargeted analytical techniques—headspace gas chromatography–ion mobility spectrometry (HS-GC-IMS) and comprehensive two-dimensional gas chromatography–mass spectrometry (GC × GC-MS)—to fingerprint the volatile organic compounds
Matteo Bordiga, Vincenzo Disca, Marcello Manfredi, Elettra Barberis, Francesca Carrà, Luciano Navarini, Valentina Lonzarich, Marco Arlorio   +7 more
doaj   +1 more source

A fusion strategy of multivariate flavor analysis techniques for the discrimination of aged sauce-flavor Baijiu

Food Chemistry: X
In the present work, effective methods for determining the age of sauce-flavor Baijiu by multivariate data analysis and machine learning techniques were explored.
Dan Wang, Yan Chen, Xinyu Ma, Xiaobing Zhang, Ji Zhang, Siqian Guo, Jingming Li, Liping Xiang   +7 more
doaj   +1 more source

Thermal decomposition and atmospheric pressure chemical ionization of alanine using ion mobility spectrometry and computational study

Heliyon
This study investigates the impact of thermal decomposition on the ion mobility spectrum of L-alanine using ion mobility spectrometry (IMS) and computational methods.
Manijeh Tozihi, Hamed Bahrami, Masoumeh Garmabdashti   +2 more
doaj   +1 more source

Geographical authentication of saffron by chemometrics applied to the ion mobility spectrometry data

Food Chemistry: X
There is a lack of a reliable tool for quickly determining the geographical origins of saffron (SFR). Ion mobility spectrometry (IMS) has emerged as a promising method for rapid authentication.
Nayereh Shamshiri, Reza Fattahi, Ahmad Mani-Varnosfaderani, Mohsen Barzegar, Mohammad Ali Sahari   +4 more
doaj   +1 more source

Reference library for suspect screening of environmental toxicants using ion mobility spectrometry-mass spectrometry

Communications Chemistry
Due to the potential health risks related to chemical exposure, rapidly assessing xenobiotic molecules in the environment and those already in the body is imperative.
Devin Teri, Noor A. Aly, James N. Dodds, Jian Zhang, Paul A. Thiessen, Evan E. Bolton, Kara M. Joseph, Antony J. Williams, Emma L. Schymanski, Ivan Rusyn, Erin S. Baker   +10 more
doaj   +1 more source