Results 11 to 20 of about 160,027 (159)

An entropic mechanism of generating selective ion binding in macromolecules. [PDF]

open access: yesPLoS Computational Biology, 2013
Several mechanisms have been proposed to explain how ion channels and transporters distinguish between similar ions, a process crucial for maintaining proper cell function.
Michael Thomas   +2 more
doaj   +1 more source

Structural plasticity of the selectivity filter in a nonselective ion channel

open access: yesIUCrJ, 2021
The sodium potassium ion channel (NaK) is a nonselective ion channel that conducts both sodium and potassium across the cellular membrane. A new crystallographic structure of NaK reveals conformational differences in the residues that make up the ...
Raktim N. Roy   +8 more
doaj   +1 more source

Ion channels and ion selectivity [PDF]

open access: yesEssays in Biochemistry, 2017
Specific macromolecular transport systems, ion channels and pumps, provide the pathways to facilitate and control the passage of ions across the lipid membrane. Ion channels provide energetically favourable passage for ions to diffuse rapidly and passively according to their electrochemical potential.
openaire   +2 more sources

Ion Selectivity in the Selectivity Filters of Acid-Sensing Ion Channels [PDF]

open access: yesScientific Reports, 2015
Sodium-selective acid sensing ion channels (ASICs), which belong to the epithelial sodium channel (ENaC) superfamily, are key players in many physiological processes (e.g. nociception, mechanosensation, cognition, and memory) and are potential therapeutic targets.
Todor Dudev, Carmay Lim
openaire   +2 more sources

Perspectives on: Ion selectivity [PDF]

open access: yesJournal of General Physiology, 2011
The purpose of the Perspectives in General Physiology is to provide a forum where scientific uncertainties or controversies are discussed in an authoritative, yet open manner. The Perspectives are solicited by the editors—often based on recommendations by members of the editorial advisory board.
openaire   +2 more sources

Ion-selective electrodes [PDF]

open access: yesPostgraduate Medical Journal, 1999
Sir, In their review of hyponatraemia, Gill and Leese1 identify pseudohyponatraemia as a methodological problem which can lead to a spuriously low sodium. However, their assertion that this is not a problem when an ion-selective electrode (ISE) is used for sodium analysis needs clarification. Two types of methods using ISEs are currently in use within
openaire   +2 more sources

Structural and thermodynamic properties of selective ion binding in a K+ channel.

open access: yesPLoS Biology, 2007
Thermodynamic measurements of ion binding to the Streptomyces lividans K(+) channel were carried out using isothermal titration calorimetry, whereas atomic structures of ion-bound and ion-free conformations of the channel were characterized by x-ray ...
Steve W Lockless   +2 more
doaj   +1 more source

Separation mechanism, selectivity enhancement strategies and advanced materials for mono-/multivalent ion-selective nanofiltration membrane

open access: yesAdvanced Membranes, 2022
Mono-/multivalent ion-selective separation has become a common requirement at the water-energy nexus, including energy storage and conversion, water purification, and sustainable industrial processes.
Dan Lu   +5 more
doaj   +1 more source

The structure of a potassium-selective ion channel reveals a hydrophobic gate regulating ion permeation

open access: yesIUCrJ, 2020
Protein dynamics are essential to function. One example of this is the various gating mechanisms within ion channels, which are transmembrane proteins that act as gateways into the cell.
Patricia S. Langan   +7 more
doaj   +1 more source

Potassium-selective channelrhodopsins

open access: yesBiophysics and Physicobiology, 2023
Since their discovery 21 years ago, channelrhodopsins have come of age and have become indispensable tools for optogenetic control of excitable cells such as neurons and myocytes.
Elena G. Govorunova   +2 more
doaj   +1 more source

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