Results 71 to 80 of about 9,952,830 (307)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Elemental analysis of geological materials by a glow discharge mass spectrometry

Стандартные образцы, 2017
Advances of elemental analysis in geology are defined by the development and improvement ofphysical, instrumental methods of chemical analysis. New instrumental methods - emission spectrometry and mass spectrometry with inductively coupled plasma (ICP ...
A. I. Hanchuk, G. G. Siharulidze, K. S. Fokin, Y. A. Karpov   +3 more
doaj  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Research on Negative Helium Ion Beam Generation Technology

Yuanzineng kexue jishu
Tandem accelerator can generate MeV-level positive ion beam, of which He ion beam can be used for experimental research and industrial applications such as ion beam analysis and ion implantation, which is an indispensable ion beam for tandem accelerator.
CHEN Haonan1, 2, CUI Baoqun1, 2, TANG Bing1, 2, CHEN Lihua1, 2, MA Ruigang1, 2, MA Yingjun1, 2, MA Xie1, 2, ZHANG Yifan1, 2, ZHAO Jiange1, 2, WANG Yunfeng1, 2, YANG Chao1, 2, YU Rongkai1, 2
doaj   +1 more source

Positive Heavy-Ion Sources [PDF]

, 1985
Ion sources were developed soon after the discovery of ions in gas discharges in the late 1800s (Va 77). The initial uses were for mass spectrometry and for nuclear physics accelerators. In recent years, more versatile accelerator sources have been required to meet the need for a broad range of ion species, intensities, and duty factors and to fit the ...
openaire   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Optimization of Ion Beam Elements Using Mathematical Transport Formalism

Journal of Applied Science and Engineering
In the study we report the features and ideal stable operating conditions of the ion source and the accelerator’s beam behavior of a nuclear microprobe at a laboratory for accelerator-based science (LABS) laboratory, i.e., iThemba LABS, South Africa ...
Mohamed Eisa, J.L. Conradie, C. Mtshali, N. Mongwaketsi, M. Maaza   +4 more
doaj   +1 more source

RF broad-beam low-energy ion source with electron compensation [PDF]

Tekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2010
Characteristics of single-grid RF ion source with 250 mm beam diameter and 1A beam current have been studied. Energy distribution functions of electrons and ions emitted by the source have been measured.
Zykov A. V., Rafalskyi D. V., Dudin S. V.   +2 more
doaj  

An Outlook on Lithium Ion Battery Technology

ACS Central Science, 2017
Lithium ion batteries as a power source are dominating in portable electronics, penetrating the electric vehicle market, and on the verge of entering the utility market for grid-energy storage.
A. Manthiram
semanticscholar   +1 more source