Results 51 to 60 of about 125,698 (307)

A Conjoined Rectilinear Collision Cell and Pulsed Extraction Ion Trap with Auxiliary DC Electrodes.

open access: yes, 2023
Ion traps are routinely directly coupled to mass analyzers, where they serve to suitably cool and shape an ion population prior to pulsed extraction into the analyzer proper.
Dmitry, Grinfeld   +7 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

3D-Printable Model of a Particle Trap: Development and Use in the Physics Classroom

open access: yesJournal of Open Hardware, 2019
Quadrupole ion traps are modern and versatile research tools used in mass spectrometers, in atomic frequency and time standards, in trapped ion quantum computing research, and for trapping anti-hydrogen ions at CERN.
Lachlan McGinness   +7 more
doaj   +1 more source

Experimental Methods for Trapping Ions Using Microfabricated Surface Ion Traps [PDF]

open access: yesJournal of Visualized Experiments, 2017
Ions trapped in a quadrupole Paul trap have been considered one of the strong physical candidates to implement quantum information processing. This is due to their long coherence time and their capability to manipulate and detect individual quantum bits (qubits).
Hong, Seokjun   +4 more
openaire   +2 more sources

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Fragmentations of protonated benzaldehydes via intermediate ion/molecule complexes

open access: yes, 1986
Filges U, Grützmacher H-F. Fragmentations of protonated benzaldehydes via intermediate ion/molecule complexes. Organic Mass Spectrometry.
U. Filges   +3 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

[2]Catenanes Displaying Switchable Gin-Trap-Like Motion

open access: yes, 2018
Sodium ion-controlled switching from “folded” to “linear” states results in significant changes in the molecular shape of a [2]­catenane, such that it mimics the operation of a gin trap, with a fluorescent alarm signal appearing when pyrene side arms ...
Chien-Chen Lai (499920)   +5 more
core   +3 more sources

Paul İyon Tuzağında Tek İyon Dinamiği

open access: yesSüleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, 2015
Özet: Bu çalışmada, iyonları elektrostatik tuzaklamaya dayalı Paul tuzağı içindeki iyon dinamikleri incelenmiştir. Paul tuzağı DC ve AC gerilim kombinasyonu ile kuadrupol elektrotların beslenmesi temeline dayanmaktadır.
Hüsnü AKSAKAL, Serkan AVCI
doaj  

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