Results 41 to 50 of about 500,675 (290)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 2016 Herein we report the synthesis of a series of poly(4-alkyl-1-vinyl-1,2,4-triazolium) poly(ionic liquid)s either via straightforward free radical polymerization of their corresponding ionic liquid monomers, or via anion metathesis of the polymer ...
Yuan, Jiayin, Zhang, Weiyi
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Mechanical Properties of Paper Saturated With a Hydrophobic Ionic Liquid
BioResources, 2023 Research into paper-based devices and ionic liquids has increased considerably in the past few years. Thus, the combination of paper-based devices with ionic liquids is also becoming an increasingly frequent research subject.
Christiane Helbrecht +5 more
doaj +2 more sources
Separations, 2019 There are many advantages to using ionic liquids as solvents or catalysts in chemical processes. Their non-volatile characteristic and high cost, however, can pose economic, environmental, and long-term health concerns.
Cynthia A. Corley, Scott T. Iacono
doaj +1 more source
Lattice Model of an Ionic Liquid at an Electrified Interface
, 2017 We study ionic liquids interacting with electrified interfaces. The ionic fluid is modeled as a Coulomb lattice gas. We compare the ionic density profiles calculated using a popular modified Poisson-Boltzmann equation with the explicit Monte Carlo ...
Colla, Thiago +3 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Frontiers in NanotechnologyIn the current study, a highly efficient and affordable sensor for liquefied petroleum gas (LPG) that operates at ambient temperature was fabricated using a thin film through an easy and low-cost approach. To achieve this objective, MoTe2 was synthesized
Ankit Singh +6 more
doaj +1 more source
Volumetric and acoustic studies of cefazolin sodium and ceftriaxone sodium in aqueous ionic liquid, 1-octyl-3-methylimidazolium bromide at T= 298.15 K [PDF]
شیمی کاربردی روز, 2018 The density (d) and speed of sound (u) for systems containing{cefazolin sodium+ ionic liquid (1-octyl-3-methyl imidazolium bromide, [OMIm] Br) + H2O} and {ceftriaxone sodium+ ionic liquid (1-octyl-3-methyl imidazolium bromide, [OMIm] Br) + H2O}have been ...
Hemayat shekaari +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source