Results 51 to 60 of about 497,812 (299)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Liquid - liquid flows in microchannels [PDF]

, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011), Angeli, P, Dore, V, Tsaoulidis, D   +3 more
core  

Phase behaviour and dynamics in primitive models of molecular ionic liquids [PDF]

, 2011
The phase behaviour and dynamics of molecular ionic liquids are studied using primitive models and extensive computer simulations. The models account for size disparity between cation and anion, charge location on the cation, and cation-shape anisotropy,
Camp, P. J., Ganzenmüller, G. C.
core   +5 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The effect of ionic liquid on the solubility of polyetheretherketone (PEEK)

Journal of Ionic Liquids
This paper aims to investigate the suitability of ionic liquids to be used as a co-solvent along with a few common solvents which are dimethyl sulfoxide (DMSO), acetonitrile, and water as the primary solvent to dissolve polyetheretherketone (PEEK).
Norazzah Afizah Jailani, Ainul Haqeem Abdul Jamil, Mohd Hilmi Noh, Muhammad Moniruzzaman   +3 more
doaj   +1 more source

Structure and ionic conductivity of ionic liquid embedded PEO- LiCF3SO3 polymer electrolyte

AIP Advances, 2014
In this paper we have reported electrical and other physical properties of polyethylene oxide (PEO) - LiCF3SO3 polymer electrolytes embedded with 1-ethyl-3-methylimidazolium trifluoromethanesulfonate ionic liquid. The addition of the ionic liquid to PEO-
A. Karmakar, A. Ghosh
doaj   +1 more source

Ionic Capillary Evaporation in Weakly Charged Nanopores

, 2010
Using a variational field theory, we show that an electrolyte confined to a neutral cylindrical nanopore traversing a low dielectric membrane exhibits a first-order ionic liquid-vapor pseudo-phase-transition from an ionic-penetration "liquid" phase to an
C. Holm, D. A. McQuarrie, G. Wagner, John Palmeri, Manoel Manghi, Sahin Buyukdagli   +5 more
core   +1 more source

From colloidal dispersions to colloidal pastesthrough solid–liquid separation processes [PDF]

, 2005
Solid–liquid separation is an operation that starts with a dispersion of solid particles in a liquid and removes some of the liquid from the particles, producing a concentrated solid paste and a clean liquid phase.
Botet, Robert, Cabane, Bernard, Madeline, J.B., Martin, Céline, Meireles, Martine, Persello, J, Schweins, R   +6 more
core   +6 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Prospects and Design Insights of Neat Ionic Liquids as Supercapacitor Electrolytes

Frontiers in Energy Research, 2021
Ionic liquids present an opportunity to design efficient electrolytes for supercapacitors, which are among the most extensively studied electrochemical energy storage systems. Ionic liquids are promising candidates for supercapacitor electrolytes because
Kallidanthiyil Chellappan Lethesh, Musbaudeen O. Bamgbopa, Rahmat Agung Susantyoko   +2 more
doaj   +1 more source