Results 191 to 200 of about 15,472 (293)

A Prussian Blue Nanozyme‐Adjuvanted Vaccine Presenting Phosphocholine Antigens for Induction of Immunotolerance in Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study developed a novel nano‐vaccine (Ferritin‐PC@PBNZs) comprising a ferritin‐based scaffold for the multivalent display of phosphorylcholine (PC) antigens, integrated with Prussian blue nanozymes (PBNZs) as a potent adjuvant. By leveraging the ferritin carrier for high‐density and ordered antigen display, the nano‐vaccine significantly augments ...
Jingyi Sheng, Yubo Huang, Xinyue Li, Yin Liu, Yuehuang Wu, Yuxin Zhang, Ning Gu   +6 more
wiley   +1 more source

How active ingredient localisation in plant tissues determines the targeted pest spectrum of different chemistries [PDF]

, 2016
Abbott, Alakoskela, Annan, Baker, Bos, Bromilow, Brück, Buchholz, Buchholz, Börner, Camenisch, Chu, Copeland, Daniels, De Duve, Freeman, Hauser, Horobin, Jeschke, Johnson, Kleier, Kliot, Kornhuber, Li, Maienfisch, Mayer, Miles, Miller, Mittler, O'Sullivan, Pabba, Powell, Powell, Silver, Stepensky, Tischbirek, Tjallingii, Trapp, Trapp, Trapp, Trapp, Trapp, Trapp, Trapp, Trapp, Trapp, Walling, Wondafrash, Zabkiewicz, Zhou   +49 more
core   +1 more source

Photocatalytic Micro/Nanomotors Functioning in the Near‐Infrared Window for Biomedical Applications

Advanced Science, EarlyView.
This review focuses on near‐infrared responsive photocatalytic micro/nanomotors based on inorganic materials, with particular emphasis on minimally invasive biomedical applications. It discusses material strategies for achieving near‐infrared responsiveness, including heterostructure construction, upconversion nanoparticle integration, defect ...
Yufen Chen, João Marcos Gonçalves, Katherine Villa   +2 more
wiley   +1 more source

Multivalent ionizable lipid-polypeptides for tumor-confined mRNA transfection. [PDF]

Bioact Mater
Zhao X, Zhang Y, Wang X, Fu Z, Zhong Z, Deng C.   +5 more
europepmc   +1 more source

Ionizable Lipid Nanoparticle-Mediated Delivery of Plasmid DNA in Cardiomyocytes. [PDF]

Int J Nanomedicine, 2022
Scalzo S, Santos AK, Ferreira HAS, Costa PA, Prazeres PHDM, da Silva NJA, Guimarães LC, E Silva MM, Rodrigues Alves MTR, Viana CTR, Jesus ICG, Rodrigues AP, Birbrair A, Lobo AO, Frezard F, Mitchell MJ, Guatimosim S, Guimaraes PPG.   +17 more
europepmc   +1 more source

GPX4 Inhibitor Resistance and Metastatic Features in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study establishes breast cancer cell lines that are resistant to glutathione peroxidase 4 inhibitors (GPX4i) in vitro and investigates the metastatic capacity of the GPX4i‐resistant versus parental lines in vivo. GPX4i‐resistant cells survive upon intravenous injection, but lose capacity to spontaneously metastasize.
Marie Sabatier, Mayher Kaur, Milena Chaufan, Felix‐Levin Hormann, Luiza Martins Nascentes Melo, Mario Palma, Jordan Torpey, Yanshan Liang, Alanis Carmona, Cameron Fraser, Midori Flores, Krystina J. Szylo, Mahsa Yavari, Sheng Hui, Alpaslan Tasdogan, Sven Heiles, Jessalyn M. Ubellacker   +16 more
wiley   +1 more source

TransMA: an explainable multi-modal deep learning model for predicting properties of ionizable lipid nanoparticles in mRNA delivery. [PDF]

Brief Bioinform
Wu K, Wang Z, Yang X, Chen Y, Mastrogiovanni F, Zhang J, Liu L.   +6 more
europepmc   +1 more source

Production, Characterization, and Assessment of Permanently Cationic and Ionizable Lipid Nanoparticles for Use in the Delivery of Self-Amplifying RNA Vaccines. [PDF]

Pharmaceutics, 2023
Kairuz D, Samudh N, Ely A, Arbuthnot P, Bloom K.   +4 more
europepmc   +1 more source

mRNA rescues neonatal acidemia while mice report no aftereffects. [PDF]

, 2019
Shang, Yonglei, Zhao, Weian, Zimak, Jan
core  

FomA‐Containing Outer Membrane Vesicles of Fusobacterium Nucleatum Facilitate Bladder Cancer Lymphatic Metastasis via IL‐6‐Dependent M2b Macrophage Polarization

Advanced Science, EarlyView.
Urinary Fusobacterium nucleatum–derived outer membrane vesicles are shown to promote bladder cancer lymphatic metastasis. The vesicle protein FomA activates TLR2/NF‐κB signaling in tumor cells, induces IL‐6 secretion, and drives M2b macrophage polarization and VEGF‐C–dependent lymphangiogenesis, revealing a microbiota‐driven mechanism linking tumor ...
Wentai Shangguan, Weijia Li, Wenxue Huang, Jilin Wu, Yao Yu, Yiyao Huang, Lin Yang, Ming Xie, Qishen Yang, Jun Zheng, Yuexuan Zhu, Qi Sun, Biao Li, Leqian Li, Zongwei Wang, Jie Zhao, Peng Wu, Bisheng Cheng   +17 more
wiley   +1 more source