Mapping Hsp104 interactions using cross‐linking mass spectrometry
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal+3 more
wiley +1 more source
Studying the Process of the Internal Combustion Engine Exhaust Gas Purification by an Electric Pulse
The article deals with method of purifying the exhaust gases in an automobile muffler or other transport equipment using electrical pulses. Electrical pulses are formed between the two ring electrodes (anode and cathode) installed in series along the gas
Adil Kadyrov+5 more
doaj +1 more source
Ionization in Atmospheres of Brown Dwarfs and Extrasolar Planets V: Alfvén Ionization [PDF]
Observations of continuous radio and sporadic X-ray emission from low-mass objects suggest they harbour localized plasmas in their atmospheric environments. For low-mass objects, the degree of thermal ionization is insufficient to qualify the ionized component as a plasma, posing the question: what ionization processes can efficiently produce the ...
arxiv +1 more source
Establishment and biological characterization of radioresistant colorectal cancer cell lines
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu+10 more
wiley +1 more source
ULTRASONIC EFFECT ON ELECTRIC SPARK FORMING AND DEVELOPMENT IN ELECTROACOUSTIC SPRAYING
Introduction. The electroacoustic application of wear-resistance coatings is studied. The work objective is to obtain a mathematical model of the ultrasonic effect on the formation and development of an electric spark occurring in the process of the ...
S. B. Kudryashev, A. A. Zakalyuzhny
doaj +1 more source
Electron-Impact Ionization of Heavy Atoms Using the Time-Dependent Close-Coupling Method
The time-dependent close-coupling method has been recently applied to calculate electron-impact direct ionization cross sections for the Kr, W, and Pb atoms. An overview is presented for these three heavy neutral atom systems.
Michael S. Pindzola+2 more
doaj +1 more source
Shining A Light On Galactic Outflows: Photo-Ionized Outflows [PDF]
We study the ionization structure of galactic outflows in 37 nearby, star forming galaxies with the Cosmic Origins Spectrograph on the Hubble Space Telescope. We use the O I, Si II, Si III, and Si IV ultraviolet absorption lines to characterize the different ionization states of outflowing gas. We measure the equivalent widths, line widths, and outflow
arxiv +1 more source
Modeling of Ionization in a Spherical Surface Ionizer
A Monte Carlo method-based model of a hot cavity surface ion source with a spherically shaped ionizer is presented. A numerical code enables studies of ion source efficiency as a function of an extraction voltage, geometry of the ionizer and its temperature, the size of extraction aperture and many other factors.
openaire +2 more sources
Possible role of human ribonuclease dicer in the regulation of R loops
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik+2 more
wiley +1 more source
Predicting Protein Binding of Drugs Using Abraham Parameters: Effect of Ionization
Background and purpose: Protein binding (PB) is an important pharmacokinetic parameter in drug discovery and development. In past years Abraham parameters were used to predict some physicochemical and pharmacokinetic properties of drugs.
Shadi Shayanfar, Ali Shayanfar
doaj